Amphiregulin Protein (AREG)
Quick Overview for Amphiregulin Protein (AREG) (ABIN7318151)
Target
See all Amphiregulin (AREG) ProteinsProtein Type
Origin
Source
Purity
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Purpose
- Recombinant Human Amphiregulin/AREG Protein
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Sequence
- Ser101-Lys198
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Characteristics
- Recombinant Human Amphiregulin is produced by our E.coli expression system and the target gene encoding Ser101-Lys198 is expressed.
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Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
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Amphiregulin (AREG) (Active) protein
AREG Origin: Human Host: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS-PAGE Func Active
Amphiregulin (AREG) (AA 101-187) (Active) protein (hFc Tag)AREG Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
Amphiregulin (AREG) (AA 100-248) (Active) protein (hFc Tag)AREG Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
Amphiregulin (AREG) (AA 1-252) protein (GST tag)AREG Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Amphiregulin (AREG) (AA 101-198) protein (His tag)AREG Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA
Amphiregulin (AREG) (AA 20-187) protein (Fc Tag)AREG Origin: Human Host: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Please refer to the printed manual for detailed information.
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Buffer
- Lyophilized from a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.4.
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Storage
- 4 °C,-20 °C,-80 °C
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Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- Amphiregulin (AREG)
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Alternative Name
- Amphiregulin/AREG
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Background
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Background: Amphiregulin (AREG) is a single-pass membrane protein with 252 amino acids. AREG belongs to the amphiregulin family, which contains 1 EGF-like domain. AREG is expressed in a variety of tissues including ovary, placenta, lung, kidney, stomach, colon, and breast. It is related to Epidermal Growth Factor (EGF) and Transforming Growth Factor Alpha (TGF-alpha). As an EGF-related growth factor, AREG interacts with the EGF/TGF-alpha receptor to promote the growth of normal epithelial cells and inhibits the growth of certain aggressive carcinoma cell lines. AREG may also play a protective role in Bleomycin-Induced Pneumopathy.
Synonym: Amphiregulin, AR, Colorectum Cell-Derived Growth Factor, CRDGF, AREG, SDGF, AREGB
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Molecular Weight
- 11.4 kDa
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UniProt
- P15514
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Pathways
- RTK Signaling, EGFR Signaling Pathway
Target
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