ANG Protein (AA 25-147)
Quick Overview for ANG Protein (AA 25-147) (ABIN7318153)
Target
See all ANG ProteinsProtein Type
Origin
Source
Purity
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Protein Characteristics
- AA 25-147
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Purpose
- Recombinant Human Angiogenin/ANG Protein
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Sequence
- Gln25-Pro147
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Characteristics
- Recombinant Human Angiogenin is produced by our E.coli expression system and the target gene encoding Gln25-Pro147 is expressed.
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Sterility
- 0.2 μm filtered
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Endotoxin Level
- < 1.0 EU per μg of the protein as determined by the LAL method.
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Biological Activity Comment
- Not validated for activity
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Angiogenin (ANG) (AA 25-147) protein (GST tag)
ANG Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Angiogenin (ANG) (AA 25-147) protein (His-IF2DI Tag)ANG Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
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Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween 80 are added as protectants before lyophilization. -
Storage
- 4 °C,-20 °C,-80 °C
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Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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Expiry Date
- 12 months
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- ANG (Angiogenin (ANG))
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Alternative Name
- Angiogenin/ANG
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Background
- ANG,Angiogenin,RNASE5,RNase 5,Ribonuclease 5,Angiogenin belongs to the pancreatic ribonuclease family. Angiogenin is primarily expressed in the liver. It may act as a tRNA-specific ribonuclease that abolishes protein synthesis by specifically hydrolyzing cellular tRNAs. Angiogenin is a potent stimulator of new blood vessel formation. And Angiogenin is endocytosed and translocated to the nucleus by binding to actin on the surface of endothelial cells. Angiogenic activity is regulated by interaction with RNH1 in vivo. In addition, Angiogenin is associated with susceptibility to amyotrophic lateral sclerosis, which is a degenerative disorder of motor neurons in the cortex, brain stem and spinal cord.
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Molecular Weight
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Calculated MW: 14.3 kDa
Observed MW: 14 kDa
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Gene ID
- 283
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UniProt
- P03950
Target
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