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Annexin VIII Protein (His tag)

This Recombinant Annexin VIII protein is produced in Escherichia coli (E. coli).
Catalog No. ABIN7317192

Quick Overview for Annexin VIII Protein (His tag) (ABIN7317192)

Target

See all Annexin VIII (ANXA8) Proteins
Annexin VIII (ANXA8) (Annexin A8 (ANXA8))

Protein Type

Recombinant

Origin

  • 9
  • 3
  • 1
  • 1
  • 1
  • 1
Human

Source

  • 7
  • 4
  • 3
  • 2
Escherichia coli (E. coli)

Purity

> 95 % as determined by reducing SDS-PAGE.
  • Purification tag / Conjugate

    This Annexin VIII protein is labelled with His tag.

    Purpose

    Recombinant Human Annexin A8/ANXA8 Protein (His Tag)

    Sequence

    Met 1-Pro327

    Characteristics

    A DNA sequence encoding the human ANXA8 (AAH73755.1) (Met1-Pro327) was expressed with a polyhistidine tag at the N-terminus.
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    Product
    Expression System
    Conjugate
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    Expression System HEK-293 Cells
    Conjugate His tag
    Origin Human
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    Origin Human
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  • Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Please refer to the printed manual for detailed information.

    Buffer

    Lyophilized from sterile PBS, pH 7.4

    Storage

    4 °C,-20 °C,-80 °C

    Storage Comment

    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • Target

    Annexin VIII (ANXA8) (Annexin A8 (ANXA8))

    Alternative Name

    Annexin A8/ANXA8

    Background

    Background: DPEP2 (MBD-2) belongs to the membrane-bound dipeptidase family. There are three members of this family as membrane-bound dipeptidase-1 (MBD-1),membrane-bound dipeptidase-2 (MBD-2) and membrane-bound dipeptidase-3 (MBD-3).MBD-2 is expressed at highest levels in lung, heart, and testis and at some what lower levels in spleen.MBD-2 is membrane-bound through a glycosylphosphatidyl-inositol linkage and probably is a metalloprotease which hydrolyzes leukotriene D4 (LTD4) into leukotriene E4 (LTE4).It is generally recognized that rapid cleavage of LTD4 is important in inactivating the broncho-and vaso-constrictive effects of cysteinyl LTs in asthmatic and inflammatory processes.

    Synonym: Annexin A8, Annexin VIII, Annexin-8, Vascular Anticoagulant-Beta, VAC-Beta, ANXA8, ANX8

    Molecular Weight

    39.1 kDa
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