AGR3 Protein (AA 21-165) (His tag)

Catalog No. ABIN7320852

This Recombinant AGR3 protein is produced in HEK-293 Cells.

Quick Overview for AGR3 Protein (AA 21-165) (His tag) (ABIN7320852)

Target: AGR3 (Anterior Gradient 3 (AGR3))

Protein Type: Recombinant

Origin: Mouse

Source: HEK-293 Cells

Purity: > 95 % as determined by reducing SDS-PAGE.

Product Details

Protein Characteristics: AA 21-165

Purification tag / Conjugate: This AGR3 protein is labelled with His tag.

Purpose: Recombinant Mouse AGR3 Protein (His Tag)

Sequence: Ile21-Leu165

Characteristics: Recombinant Mouse AGR3 is produced by our Mammalian expression system and the target gene encoding Ile21-Leu165 is expressed with a 6His tag at the C-terminus.

Sterility: 0.2 μm filtered

Endotoxin Level: < 1.0 EU per μg of the protein as determined by the LAL method.

Biological Activity Comment: Not validated for activity

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Supplied as a 0.2 μm filtered solution of PBS, 50 % Glycerol, pH 7.4.

Preservative: Without preservative

Storage: -20 °C

Storage Comment: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

Expiry Date: 6 months

Target Details

Target: AGR3 (Anterior Gradient 3 (AGR3))

Alternative Name: AGR3

Background: AG3,AGR3,Anterior gradient protein 3,BCMP11,Anterior gradient protein 3 (AGR3) is an 18 kDa member of the AGR family of proteins. It is expressed in the ciliated cells of the airway epithelium, not detected in the mucous cells. Mature human AGR3 shares 92 % amino acid sequence identity with mouse AGR3. It is required for calcium-mediated regulation of ciliary beat frequency and mucociliary clearance in the airway. AGR3 might be involved in the regulation of intracellular calcium in tracheal epithelial cells.

Molecular Weight:

Calculated MW: 18.1 kDa

Observed MW: 15-19 kDa

UniProt: Q8R3W7