ATG3 Protein
Quick Overview for ATG3 Protein (ABIN7318184)
Target
See all ATG3 ProteinsProtein Type
Origin
Source
Purity
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Purpose
- Recombinant Human ATG3 Protein
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Sequence
- Met 1-Met314
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Characteristics
- Recombinant Human Ubiquitin-like-conjugating Enzyme ATG3/ATG3 is produced by our E.coli expression system and the target gene encoding Met1-Met314 is expressed.
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Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
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ATG3 Autophagy Related 3 (ATG3) (AA 1-314) protein (His tag)
custom-made ATG3 Origin: Human Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
ATG3 Autophagy Related 3 (ATG3) (AA 1-314) protein (His tag)custom-made ATG3 Origin: Mouse Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
ATG3 Autophagy Related 3 (ATG3) (AA 1-287) protein (His tag)ATG3 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE ELISA, WB
ATG3 Autophagy Related 3 (ATG3) (AA 1-314) protein (GST tag)ATG3 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AA, AP
ATG3 Autophagy Related 3 (ATG3) (AA 1-314) protein (His tag)ATG3 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 85 % by SDS - PAGE SDS
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Restrictions
- For Research Use only
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Format
- Frozen, Liquid
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Buffer
- Supplied as a 0.2 μm filtered solution of 20 mM TrisHCl,150 mM NaCl,10 % Glycerol, pH 8.0.
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Storage
- -20 °C
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Storage Comment
- Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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- ATG3 (ATG3 Autophagy Related 3 (ATG3))
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Alternative Name
- ATG3
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Background
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Background: Ubiquitin-like-conjugating enzyme ATG3 (ATG3), also known as Apg3L and Apg3p, functions as a regulatory component of autophagosome biogenesis necessary for autophagy. ATG3 exhibits 98 % aa sequence identity with both its mouse and rat orthologs. It is widely expressed and has highly levels in heart, skeletal muscle, kidney, liver and placenta. As an E2-like enzyme, involves in autophagy and mitochondrial homeostasis. ATG3 catalyzes the conjugation of ATG8-like proteins to PE which is essential for autophagy. ATG3 also can catalyze the conjugation of ATG12 to itself which palys a role in mitochondrial homeostasis but not in autophagy.
Synonym: Ubiquitin-like-conjugating enzyme ATG3, Autophagy-related protein 3, APG3-like, hApg3, Protein PC3-96, ATG3, APG3, APG3L
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Molecular Weight
- 36 kDa
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UniProt
- Q9NT62
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Pathways
- Autophagy
Target
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