ATG5 Protein
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- Target See all ATG5 Proteins
- ATG5 (ATG5 Autophagy Related 5 (ATG5))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purpose
- Recombinant Human ATG5 Protein
- Sequence
- Met 1-Asp275
- Characteristics
- Recombinant Human Autophagy Related 5 Homolog is produced by our E.coli expression system and the target gene encoding Met1-Asp275 is expressed.
- Purity
- > 90 % as determined by reducing SDS-PAGE.
- Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product ATG5 Protein
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ATG5 Autophagy Related 5 (ATG5) (AA 138-275) protein (His-IF2DI Tag)
ATG5 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % by SDS-PAGE gel analyses ELISA, WB
ATG5 Autophagy Related 5 (ATG5) (AA 1-275) protein (GST tag)ATG5 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AA, AP
ATG5 Autophagy Related 5 (ATG5) (AA 176-275) protein (GST tag)ATG5 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AA, AP
ATG5 Autophagy Related 5 (ATG5) (AA 1-275) protein (Strep Tag)Crystallography grade ATG5 Origin: Mouse Host: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS
ATG5 Autophagy Related 5 (ATG5) protein (Myc-DYKDDDDK Tag)ATG5 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Restrictions
- For Research Use only
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- Format
- Frozen, Liquid
- Buffer
- Supplied as a 0.2 μm filtered solution of 20 mM Tris,0.2M NaCl,1 mM DTT,40 % glycerol, pH 8.0 .
- Storage
- -20 °C
- Storage Comment
- Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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- Target
- ATG5 (ATG5 Autophagy Related 5 (ATG5))
- Alternative Name
- ATG5 (ATG5 Products)
- Synonyms
- APG5 Protein, APG5-LIKE Protein, APG5L Protein, ASP Protein, hAPG5 Protein, ATG5 Protein, CG1643 Protein, DmAtg5 Protein, Dmel\\CG1643 Protein, atg5 Protein, 2010107M05Rik Protein, 3110067M24Rik Protein, AW319544 Protein, Apg5l Protein, Atg5l Protein, C88337 Protein, Paddy Protein, apg5l Protein, zgc:100934 Protein, ATATG5 Protein, AUTOPHAGY 5 Protein, MKP11.20 Protein, MKP11_20 Protein, autophagy related 5 Protein, Autophagy-related 5 Protein, ATG5 autophagy related 5 homolog (S. cerevisiae) Protein, autophagy related 5 L homeolog Protein, similar to S. cerevisiae ATG5 (YPL149W) which nucleates preautophagosome formation as a conjugate with Atg12 Protein, autophagy protein Apg5 family Protein, ATG5 Protein, Atg5 Protein, atg5 Protein, atg5.L Protein, APG5 Protein
- Background
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Background: ATG5 is an E2 ubiquitin ligase which is necessary for autophagy. Its expression is a relatively late event in the apoptotic process, occurring downstream of caspase activity, dramatically highly expressed in apoptotic cells. It is activated by ATG7, conjugates to ATG12 and associates with isolation membrane to form cup-shaped isolation membrane and autophagosome. The conjugate complex detaches from the membrane immediately before or after autophagosome formation is completed. ATG5 plays an important role in the apoptotic process, possibly within the modified cytoskeleton.
Synonym: Autophagy protein 5, APG5-like, Apoptosis-specific protein, APG5L, ASP, ATG5,
- Molecular Weight
- 32.4 kDa
- UniProt
- Q9H1Y0
- Pathways
- Activation of Innate immune Response, Production of Molecular Mediator of Immune Response, Autophagy
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