Cadherin 13 Protein (CDH13) (AA 1-692)
Quick Overview for Cadherin 13 Protein (CDH13) (AA 1-692) (ABIN7321153)
Target
See all Cadherin 13 (CDH13) ProteinsProtein Type
Origin
Source
Purity
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Protein Characteristics
- AA 1-692
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Purpose
- Recombinant Rat Cadherin-13/CDH13 Protein
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Sequence
- Met1-Ala692
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Characteristics
- A DNA sequence encoding the rat CDH13 (NP_620244.1)(Met1-Ala692) was expressed with six amino acids (LEVLFQ) at the C-terminus.
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Sterility
- 0.2 μm filtered
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Endotoxin Level
- < 1.0 EU per μg of the protein as determined by the LAL method.
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Biological Activity Comment
- Not validated for activity
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Cadherin 13 (CDH13) (AA 1-713) protein (GST tag)
CDH13 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Cadherin 13 (CDH13) (AA 139-381) protein (His tag)CDH13 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA
Cadherin 13 (CDH13) (AA 139-693) protein (His-IF2DI Tag)CDH13 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA
Cadherin 13 (CDH13) proteinCDH13 Origin: Rat Host: Escherichia coli (E. coli) Recombinant > 95 % WB, SDS, ELISA, IP
Cadherin 13 (CDH13) proteinCDH13 Origin: Mouse Host: Escherichia coli (E. coli) Recombinant > 95 % WB, SDS, ELISA, IP
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
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Lyophilized from sterile PBS, pH 7.4
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween 80 are added as protectants before lyophilization. -
Storage
- 4 °C,-20 °C,-80 °C
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Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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Expiry Date
- 12 months
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- Cadherin 13 (CDH13)
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Alternative Name
- Cadherin-13/CDH13
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Background
- CDH13,CDH13, also known as cadherin-13 and H Cadherin, is a member of the cadherin superfamily. CDH13 acts as a negative regulator of axon growth during neural differentiation. It also protects vascular endothelial cells from apoptosis due to oxidative stress, and is associated with resistance to atherosclerosis. CDH13 is localized to the surface of the cell membrane and is anchored by a GPI moiety, rather than by a transmembrane domain. CDH13 gene is hypermethylated in many types of cancer.
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Molecular Weight
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Calculated MW: 74.3 kDa
Observed MW: 84-96 kDa
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NCBI Accession
- NP_620244
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UniProt
- A0A096MK38
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Pathways
- EGFR Signaling Pathway, Cell-Cell Junction Organization
Target
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