Cadherin 8 Protein (CDH8) (His tag)

Catalog No. ABIN7318220

This Recombinant Cadherin 8 protein is expressed in Human Cells.

Quick Overview for Cadherin 8 Protein (CDH8) (His tag) (ABIN7318220)

Target: Cadherin 8 (CDH8)

Protein Type: Recombinant

Origin: Human

Source: Human Cells

Purity: > 90 % as determined by reducing SDS-PAGE.

Product Details

Purification tag / Conjugate: This Cadherin 8 protein is labelled with His tag.

Purpose: Recombinant Human Cadherin-8/CDH8 Protein (His Tag)

Sequence: Ala30-Met621

Characteristics: Recombinant Human Cadherin-8 is produced by our Mammalian expression system and the target gene encoding Ala30-Met621 is expressed with a 6His tag at the C-terminus.

Endotoxin Level: < 1.0 EU per μg as determined by the LAL method.

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.4.

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Target Details

Target: Cadherin 8 (CDH8)

Alternative Name: Cadherin-8/CDH8

Background:

Background: Cadherin-8 (CDH8) is a type II classical cadherin from the cadherin superfamily. Member of the Cadherin superfamily are integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Cadherin proteins are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small highly conserved C-terminal cytoplasmic domain. Cadherins are calcium dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells. The extracellular domain of CDH8 contains five cadherin domains. CDH8 is expressed in brain and is putatively involved in synaptic adhesion, axon outgrowth and guidance.

Synonym: Cadherin-8, CDH8,Nbla04261

Molecular Weight: 66.1 kDa

UniProt: P55286

Pathways: Cell-Cell Junction Organization