Calmegin Protein (CLGN) (AA 20-471) (His tag)
This Recombinant Calmegin protein is expressed in HEK-293 Cells.
Catalog No. ABIN7318224
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Quick Overview for Calmegin Protein (CLGN) (AA 20-471) (His tag) (ABIN7318224)
Target
See all Calmegin (CLGN) Proteins
Calmegin (CLGN)
Protein Type
Recombinant
Origin
Human
Source
HEK-293 Cells
Purity
> 90 % as determined by reducing SDS-PAGE.
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Protein Characteristics
- AA 20-471
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Purification tag / Conjugate
- This Calmegin protein is labelled with His tag.
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Purpose
- Recombinant Human Calmegin/CLGN Protein (His Tag)
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Sequence
- Glu20-Trp471
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Characteristics
- Recombinant Human Calmegin is produced by our Mammalian expression system and the target gene encoding Glu20-Trp471 is expressed with a 6His tag at the C-terminus.
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Sterility
- 0.2 μm filtered
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Endotoxin Level
- < 1.0 EU per μg of the protein as determined by the LAL method.
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Biological Activity Comment
- Not validated for activity
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Calmegin (CLGN) (AA 1-610) protein (GST tag)
CLGN Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
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Lyophilized from a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween 80 are added as protectants before lyophilization. -
Storage
- 4 °C,-20 °C,-80 °C
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Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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Expiry Date
- 12 months
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- Calmegin (CLGN)
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Alternative Name
- Calmegin/CLGN
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Background
- CLGN,Calmegin,Calmegin (CLGN) is a member of the calreticulin family. Calmegin is a testis-specific endoplasmic reticulum chaperone protein. The functions during spermatogenesis as a chaperone for a range of client proteins that is important for sperm adhesion onto the egg zona pellucida and for subsequent penetration of the zona pellucida. It is required for normal male fertility, normal sperm migration from the uterus into the oviduct. Calmegin binds calcium ions and interacts with PDILT. Calmegin may play a role in spermatogeneisis and infertility.
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Molecular Weight
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Calculated MW: 52.9 kDa
Observed MW: 60 kDa
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Gene ID
- 1047
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UniProt
- O14967
Target
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