Cathepsin B Protein (CTSB) (His tag)
Quick Overview for Cathepsin B Protein (CTSB) (His tag) (ABIN7320464)
Target
See all Cathepsin B (CTSB) ProteinsProtein Type
Origin
Source
Purity
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Purification tag / Conjugate
- This Cathepsin B protein is labelled with His tag.
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Purpose
- Recombinant Mouse Cathepsin B/CTSB Protein (His Tag)
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Sequence
- His18-Phe339
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Characteristics
- Recombinant Mouse Cathepsin B is produced by our Mammalian expression system and the target gene encoding His18-Phe339 is expressed with a 6His tag at the C-terminus.
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Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Please refer to the printed manual for detailed information.
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Buffer
- Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
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Storage
- 4 °C,-20 °C,-80 °C
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Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- Cathepsin B (CTSB)
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Alternative Name
- Cathepsin B/CTSB
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Background
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Background: Cathepsin B (CatB) is an enzymatic protein belonging to the peptidase (or protease) families. It is the first described member of the family of lysosomal cysteine proteases. It is known to process a number of proteins, including pro and active caspases, prorenin and secretory leucoprotease inhibitor (SLPI). It is believed to participate in intracellular degradation and turnover of proteins. Cathepsin B may play a role in activation and inactivation of caspases, activation of renin and inactivation of SLPI, the key steps in apoptosis, angiotensin production, and progression of emphysema, respectively. Cathepsin B may also have a role in invasion and metastasis.
Synonym: Cathepsin B,Ctsb,Cathepsin B1
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Molecular Weight
- 36.4 kDa
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UniProt
- P10605
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Pathways
- Activation of Innate immune Response, Toll-Like Receptors Cascades
Target
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