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Cathepsin E Protein (CTSE) (His tag)

CTSE Origin: Human Host: Human Cells Recombinant > 95 % as determined by reducing SDS-PAGE.
Catalog No. ABIN7318254
  • Target See all Cathepsin E (CTSE) Proteins
    Cathepsin E (CTSE)
    Protein Type
    Recombinant
    Origin
    • 7
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Source
    • 6
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    Human Cells
    Purification tag / Conjugate
    This Cathepsin E protein is labelled with His tag.
    Purpose
    Recombinant Human Cathepsin E/CTSE Protein (His Tag)
    Sequence
    Ser20-Pro396
    Characteristics
    Recombinant Human Cathepsin E is produced by our Mammalian expression system and the target gene encoding Ser20-Pro396 is expressed with a 6His tag at the C-terminus.
    Purity
    > 95 % as determined by reducing SDS-PAGE.
    Endotoxin Level
    < 1.0 EU per μg as determined by the LAL method.
    Top Product
    Discover our top product CTSE Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Please refer to the printed manual for detailed information.
    Buffer
    Lyophilized from a 0.2 μm filtered solution of 20 mM MES, 150 mM NaCl, pH 5.5.
    Storage
    4 °C,-20 °C,-80 °C
    Storage Comment
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • Target
    Cathepsin E (CTSE)
    Alternative Name
    Cathepsin E/CTSE (CTSE Products)
    Synonyms
    CATE Protein, A430072O03Rik Protein, C920004C08Rik Protein, CE Protein, CatE Protein, CEA Protein, CEB Protein, Ctsea Protein, CTSE Protein, ce1 Protein, ce2 Protein, cate Protein, CE1 Protein, ce1-A Protein, ctse Protein, CE2 Protein, ce2-A Protein, cathepsin E Protein, cathepsin E L homeolog Protein, cathepsin E S homeolog Protein, CTSE Protein, Ctse Protein, TP03_0056 Protein, Smp_184930 Protein, ctse Protein, ctse.L Protein, ctse.S Protein
    Background

    Background: Cathepsin E (CTSE) is a gastric aspartyl protease that functions as a disulfide-linked homodimer. It is a member of the Peptidase C1 family, and has a specificity similar to that of Pepsin A and Cathepsin D. CTSE is localized to the endoplasmic reticulum and Golgi apparatus, while the mature enzyme is localized to the endosome. It is expressed abundantly in the stomach, the Clara cells of the lung and activated B-lymphocytes, and at lower levels in lymph nodes, skin and spleen. CTSE is an intracellular proteinase that have a role in immune function, activation-induced lymphocyte depletion in the thymus, neuronal degeneration and glial cell activation in the brain. Futhermore, it probably involved in the processing of antigenic peptides during MHC class II-mediated antigen presentation.

    Synonym: Cathepsin E, CTSE

    Molecular Weight
    41.8 kDa
    UniProt
    P14091
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