Cathepsin S Protein (CTSS) (His tag)
-
- Target See all Cathepsin S (CTSS) Proteins
- Cathepsin S (CTSS)
- Protein Type
- Recombinant
-
Origin
- Mouse
-
Source
- Human Cells
- Purification tag / Conjugate
- This Cathepsin S protein is labelled with His tag.
- Purpose
- Recombinant Mouse Cathepsin S/CTSS Protein (His Tag)
- Sequence
- Val18-Ile340
- Characteristics
- Recombinant Mouse Cathepsin S is produced by our Mammalian expression system and the target gene encoding Val18-Ile340 is expressed with a 6His tag at the C-terminus.
- Purity
- > 95 % as determined by SDS-PAGE
- Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product CTSS Protein
-
Cathepsin S (CTSS) (AA 1-331) protein (GST tag)
CTSS Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Cathepsin S (CTSS) (Active) protein (His tag)CTSS Origin: Mouse Host: HEK-293 Cells Recombinant > 90 % as determined by SDS-PAGE Active
Cathepsin S (CTSS) (AA 115-331) protein (His tag)Crystallography grade CTSS Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Cathepsin S (CTSS) (AA 123-340) protein (His tag)Crystallography grade CTSS Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
-
- Restrictions
- For Research Use only
-
- Format
- Lyophilized
- Reconstitution
- Please refer to the printed manual for detailed information.
- Buffer
- Lyophilized from a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.4.
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
-
- Target
- Cathepsin S (CTSS)
- Alternative Name
- Cathepsin S/CTSS (CTSS Products)
- Synonyms
- ctss-a Protein, MGC69026 Protein, ctss-b Protein, MGC80097 Protein, ctss.1 Protein, CTSS Protein, ctss Protein, cats Protein, cathepsin S Protein, cathepsin S L homeolog Protein, cathepsin S S homeolog Protein, Cathepsin S Protein, CTSS Protein, Ctss Protein, ctss.L Protein, ctss.S Protein, ctss Protein, cats Protein
- Background
-
Background: Cathepsin S is a lysosomal enzyme that belongs to the papain family of cysteine proteases. This protein is expressed by antigen presenting cells including macrophages, B-lymphocytes, dendritic cells and microglia. Moreover, cathepsin S is expressed in some epithelial cells. Compared with the abundant cathepsins B, L and H, cathepsin S shows a restricted tissue distribution, with highest levels in spleen, heart, and lung. In addition, evidences indicated that cathepsin S generates A beta from amyloidogenic fragments of beta APP in the endosomal/lysosomal compartment, and is implicated in the pathogenesis of Alzheimer's disease (AD) and Down Syndrome (DS).
Synonym: Cathepsin S, CTSS
- Molecular Weight
- 37.5 kDa
- Pathways
- Activation of Innate immune Response, Toll-Like Receptors Cascades
-
