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CTCF Protein

Recombinant CTCF protein expressed in Escherichia coli (E. coli).
Catalog No. ABIN7319104

Quick Overview for CTCF Protein (ABIN7319104)

Target

See all CTCF Proteins
CTCF (CCCTC-Binding Factor (Zinc Finger Protein) (CTCF))

Protein Type

Recombinant

Origin

  • 6
  • 2
  • 1
Human

Source

  • 3
  • 2
  • 2
  • 1
  • 1
Escherichia coli (E. coli)

Purity

> 95 % as determined by reducing SDS-PAGE.
  • Purpose

    Recombinant Human CTCF Protein

    Sequence

    Met 1-Ile154

    Characteristics

    Recombinant Human CCCTC-Binding Factor is produced by our E.coli expression system and the target gene encoding Met1-Ile154 is expressed.

    Endotoxin Level

    < 1.0 EU per μg as determined by the LAL method.
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  • Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Please refer to the printed manual for detailed information.

    Buffer

    Lyophilized from a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.4.

    Storage

    4 °C,-20 °C,-80 °C

    Storage Comment

    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • Target

    CTCF (CCCTC-Binding Factor (Zinc Finger Protein) (CTCF))

    Alternative Name

    CTCF

    Background

    Background: Transcriptional Repressor CTCF (CTCF) belongs to the CTCF Zinc-Finger Protein family. CTCF contains twelve C2H2-type zinc fingers and interacts with CHD8. CTCF is widely expressed in many tissues, and it is absent in primary spermatocytes. CTCF is involved in transcriptional regulation by binding to chromatin insulators and preventing interaction between promoter and nearby enhancers and silencers. CTCF plays an essential role in oocyte and preimplantation embryo development by activating or repressing transcription. In addition, CTCF is also indispensable in the epigenetic regulation and chromatin remodeling.

    Synonym: Transcriptional Repressor CTCF, 11-Zinc Finger Protein, CCCTC-Binding Factor, CTCFL Paralog, CTCF

    Molecular Weight

    16.9 kDa

    UniProt

    P49711
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