CTCF Protein
Quick Overview for CTCF Protein (ABIN7319104)
Target
See all CTCF ProteinsProtein Type
Origin
Source
Purity
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Purpose
- Recombinant Human CTCF Protein
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Sequence
- Met 1-Ile154
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Characteristics
- Recombinant Human CCCTC-Binding Factor is produced by our E.coli expression system and the target gene encoding Met1-Ile154 is expressed.
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Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Please refer to the printed manual for detailed information.
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Buffer
- Lyophilized from a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.4.
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Storage
- 4 °C,-20 °C,-80 °C
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Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- CTCF (CCCTC-Binding Factor (Zinc Finger Protein) (CTCF))
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Alternative Name
- CTCF
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Background
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Background: Transcriptional Repressor CTCF (CTCF) belongs to the CTCF Zinc-Finger Protein family. CTCF contains twelve C2H2-type zinc fingers and interacts with CHD8. CTCF is widely expressed in many tissues, and it is absent in primary spermatocytes. CTCF is involved in transcriptional regulation by binding to chromatin insulators and preventing interaction between promoter and nearby enhancers and silencers. CTCF plays an essential role in oocyte and preimplantation embryo development by activating or repressing transcription. In addition, CTCF is also indispensable in the epigenetic regulation and chromatin remodeling.
Synonym: Transcriptional Repressor CTCF, 11-Zinc Finger Protein, CCCTC-Binding Factor, CTCFL Paralog, CTCF
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Molecular Weight
- 16.9 kDa
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UniProt
- P49711
Target
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