CD226 Protein (CD226) (His tag)
Quick Overview for CD226 Protein (CD226) (His tag) (ABIN7319663)
Target
See all CD226 ProteinsProtein Type
Origin
Source
Purity
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Purification tag / Conjugate
- This CD226 protein is labelled with His tag.
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Purpose
- Recombinant Human CD226/DNAM-1 Protein (His Tag)
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Sequence
- Glu19-Asn247
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Characteristics
- Recombinant Human CD226 is produced by our Mammalian expression system and the target gene encoding Glu19-Asn247 is expressed with a 6His tag at the C-terminus.
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Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
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CD226 (CD226) (AA 19-247) (Active) protein (His-Avi Tag)
CD226 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
CD226 (CD226) (AA 19-252) (Active) protein (His tag)CD226 Origin: Cynomolgus Host: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
CD226 (CD226) (AA 19-247) (Active) protein (Biotin,His-Avi Tag)CD226 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
CD226 (CD226) (AA 19-247) protein (His tag,mFc Tag)CD226 Origin: Human Host: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining. AM, ADA, IA, ScA
CD226 (CD226) (AA 19-252) (Active) protein (His tag)CD226 Origin: Cynomolgus Host: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE. Active
CD226 (CD226) protein (His tag)CD226 Origin: Mouse Host: Human Cells Recombinant > 95 % as determined by SDS-PAGE
CD226 (CD226) (AA 19-247) protein (hIgG-His-tag)CD226 Origin: Human Host: Baculovirus infected Insect Cells Recombinant > 90 % SDS
CD226 (CD226) (AA 19-254) protein (Fc Tag)CD226 Origin: Mouse Host: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining. AM, ADA, IA, ScA
CD226 (CD226) proteinCD226 Origin: Human Host: Escherichia coli (E. coli) Recombinant SDS
CD226 (CD226) (Active) protein (His tag)CD226 Origin: Mouse Host: HEK-293 Cells Recombinant > 97 % as determined by SDS-PAGE Active
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Please refer to the printed manual for detailed information.
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Buffer
- Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
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Storage
- 4 °C,-20 °C,-80 °C
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Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- CD226
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Alternative Name
- CD226/DNAM-1
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Background
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Background: Human DNAX accessory molecule 1 (DNAM-1/CD226) is a 65 kDa type I transmembrane glycoprotein in the immunoglobulin superfamily. Mature human DNAM-1 contains an extracellular domain (ECD) with two Ig-like C2-set domains and a cytoplasmic region that contains motifs for binding PDZ domains and band 4.1 family proteins. DNAM-1 is expressed on multiple lymphoid and myeloid cells and interacts with CD155 and CD112. Ligation of DNAM-1 promotes the activation of NK cells, CD8+ T cells, and mast cells, dendritic cell maturation, megakaryocyte and activated platelet adhesion to vascular endothelial cells, and monocyte extravasation, it inhibits the forrmation of osteoclasts. Plateletendothelium, interactions mediated by DNAM-1, enable the metastasis of tumor cells to the lung.
Synonym: CD226 antigen, DNAX accessory molecule 1, DNAM-1, CD226, DNAM1
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Molecular Weight
- 26.8 kDa
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UniProt
- Q15762
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Pathways
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints
Target
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