Quick Overview for CD276 Protein (CD276) (Fc Tag) (ABIN7320967)
Target
See all CD276 ProteinsProtein Type
Origin
Source
Purity
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Purification tag / Conjugate
- This CD276 protein is labelled with Fc Tag.
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Purpose
- Recombinant Cynomolgus B7-H3/CD276 Protein (Fc Tag)
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Sequence
- Leu29-Glu465
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Characteristics
- Recombinant Cynomolgus CD276 Molecule is produced by our Mammalian expression system and the target gene encoding Leu29-Glu465 is expressed with a Fc tag at the C-terminus.
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Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
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CD276 (CD276) (AA 29-245) (Active) protein (His tag)
CD276 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
CD276 (CD276) (AA 27-461) (Active) protein (hFc Tag)CD276 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
CD276 (CD276) (AA 29-245) protein (His tag,mFc Tag)CD276 Origin: Human Host: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining. AM, ADA, IA, ScA
CD276 (CD276) (AA 29-245) (Active) protein (Biotin,His-Avi Tag)CD276 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
CD276 (CD276) (AA 29-248) (Active) protein (His tag)CD276 Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
CD276 (CD276) (AA 29-244) protein (Fc Tag)CD276 Origin: Mouse Host: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining. AM, ADA, IA, ScA
CD276 (CD276) (AA 28-140) protein (His-DYKDDDDK-Strep II Tag)CD276 Origin: Human Host: HEK-293T Cells Recombinant WB, SDS, ELISA, PI
CD276 (CD276) (AA 28-238) protein (His-DYKDDDDK-Strep II Tag)CD276 Origin: Human Host: HEK-293T Cells Recombinant WB, SDS, ELISA, PI
CD276 (CD276) (AA 237-461) protein (His-DYKDDDDK-Strep II Tag)CD276 Origin: Human Host: HEK-293T Cells Recombinant WB, SDS, ELISA, PI
CD276 (CD276) (AA 29-245) protein (Fc Tag,AVI tag,Biotin)CD276 Origin: Human Host: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Please refer to the printed manual for detailed information.
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Buffer
- Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
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Storage
- 4 °C,-20 °C,-80 °C
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Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- CD276
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Alternative Name
- B7-H3/CD276
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Background
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Background: CD276, also known as B7-H3, is a member of the B7 superfamily with signature IgV and IgG regions in extracellular domains. It is a type I transmembrane protein and shares 20-27 % amino acid identity with other B7 family members. B7-H3 is involved in the activation of T lymphocytes, and regulates murine bone formation. It is also reported that B7-H3 may play an important role in muscle-immune interactions, providing further evidence of the active role of muscle cells in local immunoregulatory processes. B7-H3 is expressed on T-cells, natural killer cells, and antigen presenting cells, as well as some non-immune cells, such as osteoblasts, fibroblasts, fibroblast-like synoviocytes and epithelial cells. High expression of B7-H3 in tumor vasculature also correlates with poor survival in patients, suggesting that it may play a role in tumor cell migration.
Synonym: CD276 antigen, CD276, B7 homolog 3, B7-H3,CD276
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Molecular Weight
- 74 kDa
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NCBI Accession
- XP_015308534
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Pathways
- Cancer Immune Checkpoints
Target
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