Phone:
+1 877 302 8632
Fax:
+1 888 205 9894 (Toll-free)
E-Mail:
orders@antibodies-online.com

DCL1 Protein (Fc Tag)

CD302 Origin: Rat Host: HEK-293 Cells Recombinant > 95 % as determined by SDS-PAGE
Catalog No. ABIN7321088
  • Target See all DCL1 (CD302) Proteins
    DCL1 (CD302) (CD302)
    Protein Type
    Recombinant
    Origin
    • 6
    • 5
    • 1
    • 1
    Rat
    Source
    • 4
    • 3
    • 2
    • 2
    • 2
    HEK-293 Cells
    Purification tag / Conjugate
    This DCL1 protein is labelled with Fc Tag.
    Purpose
    Recombinant Rat CD302/CLEC13A Protein (Fc Tag)
    Sequence
    Met1-His165
    Characteristics
    A DNA sequence encoding the rat CD302 (Met1-His165) was expressed, fused with the Fc region of human IgG1 at the C-terminus.
    Purity
    > 95 % as determined by SDS-PAGE
    Endotoxin Level
    < 1.0 EU per μg of the protein as determined by the LAL method
    Top Product
    Discover our top product CD302 Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Please refer to the printed manual for detailed information.
    Buffer
    Lyophilized from sterile PBS, pH 7.4
    Storage
    4 °C,-20 °C,-80 °C
    Storage Comment
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • Target
    DCL1 (CD302) (CD302)
    Alternative Name
    CD302/CLEC13A (CD302 Products)
    Synonyms
    BIMLEC Protein, CLEC13A Protein, DCL-1 Protein, DCL1 Protein, RGD1307606 Protein, MGC154447 Protein, 1110055L24Rik Protein, AI159627 Protein, CD302 molecule Protein, CD302 molecule S homeolog Protein, CD302 antigen Protein, CD302 Protein, Cd302 Protein, cd302.S Protein
    Background

    Background: CD302/CLEC13A (C-type lectin domain family 13 member A), also known as C-type lectin receptor DCL-1, is a type I transmembrane C-type lectin DCL-1/CD302. DCL-1 protein was highly conserved among the human, mouse, and rat orthologs. DCL-1 ectodomain contains only one CRD, whereas other type I transmembrane C-type lectins contain more than one domain (e.g. selectins and MMR). DCL-1 CP contains several putative motifs, including a Tyr-based internalization, a cluster of acidic amino acids, and Ser and Tyr phosphorylation motifs, suggesting that DCL-1 CP mediates not only endocytosis and late endosome targeting but also signaling. DCL-1 may be another cell/matrix adhesion receptor integrated in cell adhesion complexes and that DCL-1 dysfunction may affect APC adhesion and migration, causing suppression of APC function.

    Synonym: CD302

    Molecular Weight
    43.7 kDa
    NCBI Accession
    NP_001013938
    Pathways
    Regulation of Actin Filament Polymerization
You are here: