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CD38 Protein (AA 43-300) (mFc Tag)

Recombinant CD38 protein expressed in HEK-293 Cells.
Catalog No. ABIN7319708
$513.17
Plus shipping costs $50.00
Shipping to: United States
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Quick Overview for CD38 Protein (AA 43-300) (mFc Tag) (ABIN7319708)

Target

See all CD38 Proteins
CD38

Protein Type

Recombinant

Origin

  • 27
  • 11
  • 6
  • 5
  • 1
Human

Source

  • 20
  • 9
  • 7
  • 4
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
HEK-293 Cells

Purity

> 95 % as determined by reducing SDS-PAGE.
  • Protein Characteristics

    AA 43-300

    Purification tag / Conjugate

    This CD38 protein is labelled with mFc Tag.

    Purpose

    Recombinant Human CD38 Protein (mFc Tag)

    Sequence

    Val43-Ile300

    Characteristics

    Recombinant Human CD38 is produced by our Mammalian expression system and the target gene encoding Val43-Ile300 is expressed with a mFc tag at the C-terminus.

    Sterility

    0.2 μm filtered

    Endotoxin Level

    < 1.0 EU per μg of the protein as determined by the LAL method.

    Biological Activity Comment

    Not validated for activity
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    Expression System
    Conjugate
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    Origin Human
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  • Restrictions

    For Research Use only
  • Format

    Lyophilized

    Buffer

    Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
    Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween 80 are added as protectants before lyophilization.

    Storage

    4 °C,-20 °C,-80 °C

    Storage Comment

    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

    Expiry Date

    12 months
  • Target

    CD38

    Background

    ADP-ribosyl cyclase 1,ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1,CD38,CD38 antigen,CD38 Molecule,Cyclic ADP-ribose hydrolase 1,CD38, also called ADP-ribosyl cyclase, is a Type II integral membrane protein with 301 amino acids in length that belongs to the ADP-ribosyl cyclase family.It synthesizes the second messagers cyclic ADP-ribose and nicotinate-adenine dinucleotide phosphate, the former a second messenger for glucose-induced insulin secretion. And also moonlights as a receptor in cells of the immune system. CD38 is expressed in B and T lymphocytes, osteoclasts, and in cardiac, pancreatic, liver and kidney cells. Through its production of cyclic ADP-ribose, CD38 modulates calcium-mediated signal transduction in many types of cells, including neutrophils and pancreatic beta cells.

    Molecular Weight

    Calculated MW: 56.5 kDa

    Observed MW: 70-90 kDa

    Gene ID

    952

    UniProt

    P28907
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