CD38 Protein (AA 44-301) (Fc Tag)
Quick Overview for CD38 Protein (AA 44-301) (Fc Tag) (ABIN7320968)
Target
See all CD38 ProteinsProtein Type
Origin
Source
Purity
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Protein Characteristics
- AA 44-301
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Purification tag / Conjugate
- This CD38 protein is labelled with Fc Tag.
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Purpose
- Recombinant Cynomolgus CD38/ADP-ribosyl Cyclase 1 Protein (Fc Tag)
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Sequence
- Leu44-Ile301
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Characteristics
- Recombinant Cynomolgus CD38 is produced by our Mammalian expression system and the target gene encoding Leu44-Ile301 is expressed with a Fc tag at the C-terminus.
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Sterility
- 0.2 μm filtered
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Endotoxin Level
- < 1.0 EU per μg of the protein as determined by the LAL method.
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Biological Activity Comment
- Not validated for activity
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
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Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween 80 are added as protectants before lyophilization. -
Storage
- 4 °C,-20 °C,-80 °C
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Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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Expiry Date
- 12 months
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- CD38
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Alternative Name
- CD38/ADP-ribosyl Cyclase 1
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Background
- ADP-ribosyl cyclase 1,CD38,T10,cyclic ADP-ribose hydrolase,CD38, also called ADP-ribosyl cyclase, is a Type II integral membrane protein with 301 amino acids in length that belongs to the ADP-ribosyl cyclase family.It synthesizes the second messagers cyclic ADP-ribose and nicotinate-adenine dinucleotide phosphate, the former a second messenger for glucose-induced insulin secretion. And also moonlights as a receptor in cells of the immune system. CD38 is expressed in B and T lymphocytes, osteoclasts, and in cardiac, pancreatic, liver and kidney cells. Through its production of cyclic ADP-ribose, CD38 modulates calcium-mediated signal transduction in many types of cells, including neutrophils and pancreatic beta cells.
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Molecular Weight
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Calculated MW: 57.0 kDa
Observed MW: 65-95 kDa
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UniProt
- Q5VAN0
Target
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