CD58 Protein (CD58) (Fc Tag)
Quick Overview for CD58 Protein (CD58) (Fc Tag) (ABIN7319528)
Target
See all CD58 ProteinsProtein Type
Origin
Source
Purity
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Purification tag / Conjugate
- This CD58 protein is labelled with Fc Tag.
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Purpose
- Recombinant Human LFA-3/CD58 Protein (Fc Tag)
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Sequence
- Phe29-Arg215
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Characteristics
- Recombinant Human CD58 is produced by our Mammalian expression system and the target gene encoding Phe29-Arg215 is expressed with a Fc tag at the C-terminus.
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Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Please refer to the printed manual for detailed information.
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Buffer
- Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4 .
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Storage
- 4 °C,-20 °C,-80 °C
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Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- CD58
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Alternative Name
- LFA-3/CD58
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Background
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Background: Lymphocyte function-associated antigen 3 (LFA-3/CD58) is a single-pass type I membrane protein. CD58 is widely expressed on hematopoietic and non-hematopoietic human tissue and has been found on leukocytes, erythrocytes, endothelial cells, epithelial cells and fibroblasts of human origin. It is a Ligand of the T-lymphocyte CD2 glycoprotein. This interaction is important in mediating thymocyte interactions with thymic epithelial cells, antigen-independent and -dependent interactions of T-lymphocytes with target cells and antigen-presenting cells and the T-lymphocyte rosetting with erythrocytes. In addition, the LFA-3/CD2 interaction may prime response by both the CD2+ and LFA-3+ cells.
Synonym: Lymphocyte Function-Associated Antigen 3, Surface Glycoprotein LFA-3, CD58, LFA3,Ag3, CD58 antigen
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Molecular Weight
- 48.6 kDa
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UniProt
- P19256
Target
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