CD79b Protein (His tag)

Catalog No. ABIN7321125

This Recombinant CD79b protein is produced in HEK-293 Cells.

Quick Overview for CD79b Protein (His tag) (ABIN7321125)

Target: CD79b (CD79B) (CD79b Molecule, Immunoglobulin-Associated beta (CD79B))

Protein Type: Recombinant

Origin: Rat

Source: HEK-293 Cells

Purity: > 90 % as determined by SDS-PAGE

Product Details

Purification tag / Conjugate: This CD79b protein is labelled with His tag.

Purpose: Recombinant Rat CD79B/B29 Protein (His Tag)

Sequence: Met1-Asp158

Characteristics: A DNA sequence encoding the rat CD79B (O70153) (Met1-Asp158) was expressed, fused with a polyhistidine tag at the C-terminus.

Endotoxin Level: < 1.0 EU per μg of the protein as determined by the LAL method

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from sterile PBS, pH 7.4

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Target Details

Target: CD79b (CD79B) (CD79b Molecule, Immunoglobulin-Associated beta (CD79B))

Alternative Name: CD79B/B29

Background:

Background: CD79B is a single-pass type I membrane protein. CD79B contains one Ig-like V-type domain and one ITAM domain. CD79B is required in cooperation with CD79A for initiation of the signal transduction cascade activated by the B-cell antigen receptor complex (BCR), which leads to internalization of the complex, trafficking to late endosomes and antigen presentation. CD79B enhances phosphorylation of CD79A, possibly by recruiting kinases that phosphorylate CD79A or by recruiting proteins that bind to CD79A and protect it from dephosphorylation.

Synonym: CD79B,B29/Ig-beta,Igb

Molecular Weight: 16.8 kDa

UniProt: O70153

Pathways: BCR Signaling