CD83 Protein (CD83) (AA 1-133) (His tag)

Catalog No. ABIN7320187

This Recombinant CD83 protein is produced in HEK-293 Cells.

Quick Overview for CD83 Protein (CD83) (AA 1-133) (His tag) (ABIN7320187)

Target: CD83

Protein Type: Recombinant

Origin: Mouse

Source: HEK-293 Cells

Purity: > 95 % as determined by SDS-PAGE

Product Details

Protein Characteristics: AA 1-133

Purification tag / Conjugate: This CD83 protein is labelled with His tag.

Purpose: Recombinant Mouse CD83/HB15 Protein (aa 1-133, His Tag)

Sequence: Met 1-Arg 133

Characteristics: A DNA sequence encoding the extracellular domain of mouse CD83 (O88324) (Met 1-Arg 133) was expressed, with a C-terminal polyhistidine tag.

Endotoxin Level: < 1.0 EU per μg of the protein as determined by the LAL method.

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from sterile PBS, pH 7.4

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Target Details

Target: CD83

Alternative Name: CD83/HB15

Background:

Background: The cluster of differentiation (CD) system is commonly used as cell markers in immunophynotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules which associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alter the behavior of the cell. Some CD proteins do not take part in cell signal process but have other functions such as cell adhesion. CD83 is considered as a marker of mature dendritic cells as well as an adhesion receptor that binds to resting monocytes and a subset of activated CD8+ T cells. In certain conditions, CD83 tended to dimerize or even multimerize through its aberrant intermolecular disulfide bonds. The injection of CD83-Ig can significantly enhaunce the rate of tumor growth and inhibit the T cell growth.

Synonym: CD83 Antigen, hCD83, B-Cell Activation Protein, Cell Surface Protein HB15, CD83

Molecular Weight: 13.6 kDa

UniProt: O88324