Quick Overview for CD84 Protein (CD84) (His tag) (ABIN7320706)
Target
See all CD84 ProteinsProtein Type
Origin
Source
Purity
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Purification tag / Conjugate
- This CD84 protein is labelled with His tag.
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Purpose
- Recombinant Mouse SLAMF5/CD84 Protein (His Tag)
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Sequence
- Lys22-Pro223
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Characteristics
- Recombinant Mouse SLAM family member 5 is produced by our Mammalian expression system and the target gene encoding Lys22-Pro223 is expressed with a 6His tag at the C-terminus.
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Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
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CD84 (CD84) (AA 22-225) (Active) protein (His-Avi Tag)
CD84 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
CD84 (CD84) (AA 1-328) protein (GST tag)CD84 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
CD84 (CD84) (AA 22-225) protein (mFc-His Tag)CD84 Origin: Human Host: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
CD84 (CD84) (AA 22-225) protein (His tag)CD84 Origin: Human Host: Baculovirus infected Insect Cells Recombinant > 95 % SDS
CD84 (CD84) (AA 22-221) protein (Fc Tag)CD84 Origin: Mouse Host: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
CD84 (CD84) (Active) protein (His tag)CD84 Origin: Mouse Host: HEK-293 Cells Recombinant > 97 % as determined by SDS-PAGE Active
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Please refer to the printed manual for detailed information.
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Buffer
- Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
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Storage
- 4 °C,-20 °C,-80 °C
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Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- CD84
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Alternative Name
- SLAMF5/CD84
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Background
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Background: CD84, also called SLAMF5, is a member of the CD2 subgroup of the immunoglobulin receptor superfamily. Members of this CD2 subgroup mediate signal transduction through the interaction of its immunoreceptor tyrosine-based switch motifs (ITSM) in the intracellular region and the SH2 domain of adaptor molecules SAP (SLAM-associated protein) and EAT-2 (EWS-activated transcript 2), and accordingly modulate both adaptive and innate immune responses. CD84 expression has been documented on several hematopoietic cell types, including monocytes, macrophages, dendritic cells, B lymphocytes, and platelets. Activation of cell surface CD84 initiates a signaling cascade involving its intra-cytoplasmic tyrosine residues that results in Bcl-2 upregulation, which in turn enhances cell survival. Either immunoneutralization or blockade of CD84 with a CD84 extracellular domain protein fragment induces cell death in vitro and in vivo.
Synonym: SLAM family member 5, Cd84, Leukocyte differentiation antigen CD84, Signaling lymphocytic activation molecule 5, CD84, Ly-9B, SLAMF5, CD84 antigen, CD84 Molecule, SLAM family member 5
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Molecular Weight
- 23.8 kDa
Target
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