CD8B Protein (Fc Tag)
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- Target See all CD8B Proteins
- CD8B (CD8b Molecule (CD8B))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Human Cells
- Purification tag / Conjugate
- This CD8B protein is labelled with Fc Tag.
- Purpose
- Recombinant Human CD8 Beta Chain/CD8B (C-Fc)
- Sequence
- Leu22-Pro170
- Characteristics
- Recombinant Human T-Cell Surface Glycoprotein CD8 beta Chain is produced by our Mammalian expression system and the target gene encoding Leu22-Pro170 is expressed with a Fc tag at the C-terminus.
- Purity
- >95 % as determined by reducing SDS-PAGE.
- Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product CD8B Protein
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CD8b Molecule (CD8B) (AA 1-243) protein (GST tag)
CD8B Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
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CD8b Molecule (CD8B) (AA 22-210) protein (rho-1D4 tag)Crystallography grade CD8B Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
CD8b Molecule (CD8B) (AA 22-213) protein (rho-1D4 tag)Crystallography grade CD8B Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Please refer to the printed manual for detailed information.
- Buffer
- Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.4.
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- Target
- CD8B (CD8b Molecule (CD8B))
- Alternative Name
- CD8 Beta Chain/CD8B (CD8B Products)
- Synonyms
- Cd8b Protein, Ly-3 Protein, Ly-C Protein, Lyt-3 Protein, CD8B1 Protein, LEU2 Protein, LY3 Protein, LYT3 Protein, P37 Protein, Cd8b1 Protein, CD8b molecule Protein, CD8 antigen, beta chain 1 Protein, Cd8b Protein, CD8B Protein, Cd8b1 Protein
- Background
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Background: T-Cell Surface Glycoprotein CD8β Chain (CD8 Antigen) is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. CD8 Antigen, acting as a coreceptor, and the T-cell receptor on the T lymphocyte recognize antigens displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. The functional coreceptor is either a homodimer composed of two alpha chains, or a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. Multiple alternatively spliced transcript variants encoding distinct membrane associated or secreted isoforms have been described. A pseudogene, also located on chromosome 2, has been identified.
Synonym: T-Cell Surface Glycoprotein CD8 Beta Chain, CD8b, CD8B, CD8B1
- Molecular Weight
- 43.7 kDa
- UniProt
- P10966
- Pathways
- TCR Signaling
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