CD90 Protein (THY1) (Fc Tag)

Catalog No. ABIN7194988

Product Details

Target: CD90 (THY1)

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Purification tag / Conjugate: This CD90 protein is labelled with Fc Tag.

Purpose: Recombinant Human CD90/THY-1 Protein (Fc Tag)

Sequence: Met 1-Cys130

Characteristics: A DNA sequence encoding the human THY1 (NP_006279.2) (Met1-Cys130) was expressed with the Fc region of human IgG1 at the C-terminus.

Purity: > 95 % as determined by reducing SDS-PAGE.

Endotoxin Level: < 1.0 EU per μg as determined by the LAL method.

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from sterile PBS, pH 7.4

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Target Details

Target: CD90 (THY1)

Alternative Name: CD90/THY-1 (THY1 Products)

Synonyms: CD90 Protein, CD7 Protein, T25 Protein, Thy-1 Protein, Thy-1.2 Protein, Thy1.1 Protein, Thy1.2 Protein, Thy-1 cell surface antigen Protein, thymus cell antigen 1, theta Protein, THY1 Protein, Thy1 Protein

Background:

Background: Thy-1 membrane glycoprotein, also known as Thy-1 antigen, CD90 and THY1, is a cell membrane protein which contains 1 Ig-like V-type (immunoglobulin-like) domain. It is a glycophosphatidylinositol-linked glycoprotein expressed on the surface of neurons, thymocytes, subsets of fibroblasts, endothelial cells, mesangial cells and some hematopoietic cells. It has been identified on a variety of stem cells and at varying levels in non-lymphoid tissues such as on fibroblasts, brain cells, and activated endothelial cells. Thy-1 is evolutionarily conserved, developmentally regulated, and often has dramatic effects on cell phenotype. Thy-1 is a 25-37 kDa glycosylphosphatidylinositol (GPI)-anchored protein involved in T cell activation, neurite outgrowth, apoptosis, tumor suppression, wound healing, and fibrosis. To mediate these diverse effects, Thy-1 participates in multiple signaling cascades. Thy-1 is an important regulator of cell-cell and cell-matrix interactions, with important roles in nerve regeneration, metastasis, inflammation, and fibrosis.

Synonym: CD90

Molecular Weight: 39.3 kDa

NCBI Accession: NP_006279

Pathways: Cell-Cell Junction Organization