CHI3L3 Protein (P105S) (His tag)

Catalog No. ABIN7320844

This Recombinant CHI3L3 protein is expressed in Human Cells.

Quick Overview for CHI3L3 Protein (P105S) (His tag) (ABIN7320844)

Target: CHI3L3 (Chitinase 3-Like 3 (CHI3L3))

Protein Type: Recombinant

Origin: Mouse

Source: Human Cells

Purity: > 95 % as determined by reducing SDS-PAGE.

Product Details

Protein Characteristics: P105S

Purification tag / Conjugate: This CHI3L3 protein is labelled with His tag.

Purpose: Recombinant Mouse YM1/ECF-L/Chil3 Protein (Pro105Ser)(His Tag)

Sequence: Tyr22-Tyr398(Pro105Ser)

Characteristics: Recombinant Mouse CHI3L3 is produced by our Mammalian expression system and the target gene encoding Tyr22-Tyr398(Pro105Ser) is expressed with a 6His tag at the C-terminus.

Endotoxin Level: < 1.0 EU per μg as determined by the LAL method.

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Target Details

Target: CHI3L3 (Chitinase 3-Like 3 (CHI3L3))

Alternative Name: YM1/ECF-L/Chil3

Background:

Background: Chitinase 3-like 3 gene, also known as YM1 and ECF-L, encodes a precursor protein with 398 amino acid residues with a 21 residue signal sequence. Chitinase 3-like 3 protein is a lectin that binds saccharides with a free amino group, such as glucosamine or galactosamine. Binding to oligomeric saccharides is much stronger than binding to mono- or disaccharides. Also binds heparin and G1cN oligomers, and is produced primarily by macrophages during inflammation. It has chemotactic activity for T-lymphocytes, bone marrow cells and eosinophils.

Synonym: CHI3L3, Chitinase-like protein 3, Chil3,Ym1

Molecular Weight: 43.4 kDa

UniProt: O35744