CTGF Protein (AA 27-180)

Catalog No. ABIN7318333

This Recombinant CTGF protein is expressed in HEK-293 Cells.

Quick Overview for CTGF Protein (AA 27-180) (ABIN7318333)

Target: CTGF (Connective Tissue Growth Factor (CTGF))

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Purity: > 95 % as determined by reducing SDS-PAGE.

Product Details

Protein Characteristics: AA 27-180

Purpose: Recombinant Human CTGF/CCN2 Protein

Sequence: Glu27-Ala180

Characteristics: Recombinant Human Connective tissue growth factor is produced by our Mammalian expression system and the target gene encoding Glu27-Ala180 is expressed.

Sterility: 0.2 μm filtered

Endotoxin Level: < 1.0 EU per μg of the protein as determined by the LAL method.

Biological Activity Comment: Not validated for activity

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween 80 are added as protectants before lyophilization.

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Expiry Date: 12 months

Target Details

Target: CTGF (Connective Tissue Growth Factor (CTGF))

Alternative Name: CTGF/CCN2

Background: CCN family member 2,Connective tissue growth factor,Hypertrophic chondrocyte-specific protein 24,IBP-8,IGF-binding protein 8,IGFBP-8,Insulin-like growth factor-binding protein 8,CTGF belongs to the CCN (CTGF/Cyr61/Cef10/NOVH) protein family, which is comprised of six secreted proteins that reside in the extracellular matrix (ECM). CTGF causes a variety of cellular responses including reduced cell adhesion and enhanced cell migration and proliferation. CTGF has also been shown to be essential for epithelial to mesenchymal transition (EMT), a process whereby normal functioning cells morph into ones that produce mainly scar tissue (of which collagen in the major protein component).

Molecular Weight:

Calculated MW: 16.3 kDa

Observed MW: 16-25 kDa

Gene ID: 1490

UniProt: P29279

Pathways: Regulation of Lipid Metabolism by PPARalpha, Positive Regulation of Endopeptidase Activity, Growth Factor Binding