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CRYAB Protein (His tag)

CRYAB Origin: Human Host: Escherichia coli (E. coli) Recombinant > 95 % as determined by reducing SDS-PAGE.
Catalog No. ABIN7319198
  • Target See all CRYAB Proteins
    CRYAB (Crystallin, alpha B (CRYAB))
    Protein Type
    Recombinant
    Origin
    • 7
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Source
    • 13
    • 6
    • 3
    • 1
    Escherichia coli (E. coli)
    Purification tag / Conjugate
    This CRYAB protein is labelled with His tag.
    Purpose
    Recombinant Human CRYAB Protein (His Tag)
    Sequence
    Met 1-Lys175
    Characteristics
    Recombinant Human Crystalline alpha -B chain is produced by our E.coli expression system and the target gene encoding Met1-Lys175 is expressed with a 6His tag at the C-terminus.
    Purity
    > 95 % as determined by reducing SDS-PAGE.
    Endotoxin Level
    < 1.0 EU per μg as determined by the LAL method.
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    Product
    Expression System
    Conjugate
    Origin
    Price starts at
    Expression System HEK-293 Cells
    Conjugate His tag
    Origin Human
    Price starts at $13,686.36

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  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Please refer to the printed manual for detailed information.
    Buffer
    Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.2.
    Storage
    4 °C,-20 °C,-80 °C
    Storage Comment
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • Target
    CRYAB (Crystallin, alpha B (CRYAB))
    Alternative Name
    CRYAB (CRYAB Products)
    Background

    Background: α Crystallin B Chain (CRYAB) is a cytoplasmic protein that belongs to the small heat shock protein (HSP20) family. Alpha crystallins are composed of two gene products: alpha-A and alpha-B, for acidic and basic, respectively. Alpha crystallins can be induced by heat shock and are members of the small heat shock protein (sHSP also known as the HSP20) family. Alpha crystallins acts as molecular chaperones and hold them in in large soluble aggregates. CRYAB is expressed widely in many tissues and organs. It may contribute to the transparency and refractive index of the lens. The deficiency of CRYAB is the cause of myopathy myofibrillar type 2 (MFM2) and cataract posterior polar type 2 (CTPP2).

    Synonym: Alpha-Crystallin B Chain, Alpha(B)-Crystallin, Heat Shock Protein Beta-5, HspB5, Renal Carcinoma Antigen NY-REN-27, Rosenthal Fiber Component, CRYAB, CRYA2

    Molecular Weight
    21.2 kDa
    UniProt
    P02511
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