CST3 Protein (AA 27-146)
Quick Overview for CST3 Protein (AA 27-146) (ABIN7318372)
Target
See all CST3 ProteinsProtein Type
Origin
Source
Purity
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Protein Characteristics
- AA 27-146
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Purpose
- Recombinant Human Cystatin C/CST3 Protein (Human Cells)
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Sequence
- Ser27-Ala146
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Characteristics
- Recombinant Human Cystatin C is produced by our Mammalian expression system and the target gene encoding Ser27-Ala146 is expressed.
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Sterility
- 0.2 μm filtered
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Endotoxin Level
- < 1.0 EU per μg of the protein as determined by the LAL method.
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Biological Activity Comment
- Not validated for activity
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
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Lyophilized from a 0.2 μm filtered solution of 10 mM PB, 200 mM Nacl, pH 6.5.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween 80 are added as protectants before lyophilization. -
Storage
- 4 °C,-20 °C,-80 °C
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Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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Expiry Date
- 12 months
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- CST3 (Cystatin C (CST3))
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Alternative Name
- Cystatin C/CST3
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Background
- CST3,Cystatin-3,Cystatin-C,Gamma-trace,Neuroendocrine basic polypeptide,Post-gamma-globulin,Cystatin C is a member of family 2 of the cystatin superfamily. It is ubiquitous in human tissues and body fluids and mainly used as a biomarker of kidney function. Cystatin C inhibits many cysteine proteases such as papain and Cathepsins B, H, K, L and S. As an inhibitor of cysteine proteinases, Cystatin C is thought to serve an important physiological role as a local regulator of this enzyme activity. Recently, it has been studied for its role in predicting new-onset or deteriorating cardiovascular disease. It also seems to play a role in brain disorders involving amyloid (a specific type of protein deposition), such as Alzheimer's disease.
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Molecular Weight
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Calculated MW: 13.3 kDa
Observed MW: 15 kDa
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Gene ID
- 1471
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UniProt
- P01034
Target
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