DEFB104A Protein (AA 23-72)

Catalog No. ABIN7319216

This Recombinant DEFB104A protein is expressed in Escherichia coli (E. coli).

Quick Overview for DEFB104A Protein (AA 23-72) (ABIN7319216)

Target: DEFB104A (Defensin, beta 104A (DEFB104A))

Protein Type: Recombinant

Origin: Human

Source: Escherichia coli (E. coli)

Purity: > 95 % as determined by reducing SDS-PAGE.

Product Details

Protein Characteristics: AA 23-72

Purpose: Recombinant Human DEFB104A Protein

Sequence: Glu23-Pro72

Characteristics: Recombinant Human beta-Defensin 4 is produced by our E.coli expression system and the target gene encoding Glu23-Pro72 is expressed.

Sterility: 0.2 μm filtered

Endotoxin Level: < 1.0 EU per μg of the protein as determined by the LAL method.

Biological Activity Comment: Not validated for activity

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 130 mM NaCl, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween 80 are added as protectants before lyophilization.

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Expiry Date: 12 months

Target Details

Target: DEFB104A (Defensin, beta 104A (DEFB104A))

Alternative Name: DEFB104A

Background: BD-4,Beta-Defensin 104,Beta-Defensin 4,DEFB-4,DEFB104,DEFB104A,DEFB104B,DEFB4,Defensin Beta 104,hBD-4,Defensins are cationic peptides. It is an important ingredient of the innate immune system. β-defensins are expressed on some leukocytes and epithelial surfaces. Four human β-Defensins have been identified to date: BD-1, BD-2, BD-3 and BD-4. β-defensins contain a six-cysteine motif, they forms three intra-molecular disulfide bonds. β-defensins are also chemoattractant towards immature dendritic cells and memory T cells. The β-defensin proteins are expressed as the C-terminal portion of precursors, they are released by proteolytic cleavage of a signal sequence.

Molecular Weight:

Calculated MW: 6.0 kDa

Observed MW: 9 kDa

Gene ID: 140596

UniProt: Q8WTQ1