Deoxyuridine Triphosphatase (DUT) Protein

Catalog No. ABIN7318415

This Recombinant protein is expressed in Escherichia coli (E. coli).

Quick Overview for Deoxyuridine Triphosphatase (DUT) Protein (ABIN7318415)

Target: Deoxyuridine Triphosphatase (DUT)

Protein Type: Recombinant

Origin: Human

Source: Escherichia coli (E. coli)

Purity: > 90 % as determined by reducing SDS-PAGE.

Product Details

Purpose: Recombinant Human dUTPase Protein

Sequence: Met 1-Asn164

Characteristics: Recombinant Human Deoxyuridine 5'-Triphosphate Nucleotidohydrolase,Mitochondrial is produced by our E.coli expression system and the target gene encoding Met1-Asn164 is expressed.

Endotoxin Level: < 1.0 EU per μg as determined by the LAL method.

Application Details

Restrictions: For Research Use only

Handling

Format: Frozen, Liquid

Buffer: Supplied as a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.4.

Storage: -20 °C

Storage Comment: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

Target Details

Target: Deoxyuridine Triphosphatase (DUT)

Alternative Name: dUTPase

Target Type: Viral Protein

Background:

Background: Deoxyuridine 5'-Triphosphate Nucleotidohydrolase Mitochondrial (dUTPase) belongs to the dUTPase family. dUTPase exits as a homotrimer and is involved in nucleotide metabolism. dUTPase produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA. The dUTPase increase in PCR product yield, length and fidelity enables further down-stream applications. These effects make dUTPase useful in PCR fidelity and yield-sensitive applications. dUTPase is specific for dUTP and is critical for the fidelity of DNA replication and repair.

Synonym: Deoxyuridine 5'-Triphosphate Nucleotidohydrolase Mitochondrial, dUTPase, dUTP Pyrophosphatase, DUT

Molecular Weight: 17.7 kDa