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DPEP2 Protein (Fc Tag)

DPEP2 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by reducing SDS-PAGE.
Catalog No. ABIN7317196
  • Target See all DPEP2 Proteins
    DPEP2 (Dipeptidase 2 (DPEP2))
    Protein Type
    Recombinant
    Origin
    • 4
    • 1
    • 1
    Human
    Source
    • 2
    • 1
    • 1
    • 1
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This DPEP2 protein is labelled with Fc Tag.
    Purpose
    Recombinant Human DPEP2 Protein (Fc Tag)
    Sequence
    Met 1-Ser376
    Characteristics
    A DNA sequence encoding the human DPEP2 (AAH24021.1) (Met1-Ser376) was expressed, fused with the Fc region of human IgG1 at the C-terminus.
    Purity
    > 95 % as determined by reducing SDS-PAGE.
    Endotoxin Level
    < 1.0 EU per μg as determined by the LAL method.
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  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Please refer to the printed manual for detailed information.
    Buffer
    Lyophilized from sterile PBS, pH 7.4
    Storage
    4 °C,-20 °C,-80 °C
    Storage Comment
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • Target
    DPEP2 (Dipeptidase 2 (DPEP2))
    Alternative Name
    DPEP2 (DPEP2 Products)
    Synonyms
    DIP-2 Protein, F630103D06Rik Protein, MBD-2 Protein, MBD2 Protein, dipeptidase 3 Protein, dipeptidase 2 Protein, Dipeptidase 2 Protein, DPEP3 Protein, LOC539370 Protein, LOC611083 Protein, DPEP2 Protein, Dip-2 Protein, Dpep2 Protein
    Background

    Background: DPEP2 (MBD-2) belongs to the membrane-bound dipeptidase family. There are three members of this family as membrane-bound dipeptidase-1 (MBD-1),membrane-bound dipeptidase-2 (MBD-2) and membrane-bound dipeptidase-3 (MBD-3).MBD-2 is expressed at highest levels in lung, heart, and testis and at some what lower levels in spleen.MBD-2 is membrane-bound through a glycosylphosphatidyl-inositol linkage and probably is a metalloprotease which hydrolyzes leukotriene D4 (LTD4) into leukotriene E4 (LTE4).It is generally recognized that rapid cleavage of LTD4 is important in inactivating the broncho-and vaso-constrictive effects of cysteinyl LTs in asthmatic and inflammatory processes.

    Synonym: MBD2

    Molecular Weight
    65 kDa
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