EGR1 Protein (His tag)
Quick Overview for EGR1 Protein (His tag) (ABIN7318419)
Target
See all EGR1 ProteinsProtein Type
Origin
Source
Purity
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Purification tag / Conjugate
- This EGR1 protein is labelled with His tag.
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Purpose
- Recombinant Human EGR1 Protein (His Tag)
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Sequence
- Gln282-Ser433
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Characteristics
- Recombinant Human Early growth response protein 1 is produced by our E.coli expression system and the target gene encoding Gln282-Ser433 is expressed with a 6His tag at the N-terminus.
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Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
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Early Growth Response 1 (EGR1) (AA 1-543) protein (His tag)
custom-made EGR1 Origin: Human Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Early Growth Response 1 (EGR1) (AA 1-533) protein (His tag)custom-made EGR1 Origin: Mouse Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Early Growth Response 1 (EGR1) (AA 444-543) protein (GST tag)EGR1 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Early Growth Response 1 (EGR1) (AA 282-433) protein (His-IF2DI Tag)EGR1 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA
Early Growth Response 1 (EGR1) (AA 444-543), (partial) protein (His tag)EGR1 Origin: Human Host: Yeast Recombinant > 90 % SDS
Early Growth Response 1 (EGR1) proteinEGR1 Origin: Mouse Host: Escherichia coli (E. coli) Recombinant > 95 % WB, SDS, ELISA, IP
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Please refer to the printed manual for detailed information.
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Buffer
- Lyophilized from a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.4.
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Storage
- 4 °C,-20 °C,-80 °C
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Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- EGR1 (Early Growth Response 1 (EGR1))
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Alternative Name
- EGR1
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Background
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Background: EGR-1 belongs to the EGR family of C2H2-type zinc finger proteins. It is a nuclear protein and functions as a transcriptional regulator. EGR-1 recognizes and binds to the DNA sequence 5'-CGCCCCCGC-3'(EGR-site).The products of target genes it activates are required for differentiation and mitogenesis. Studies suggest this is a tumor suppressor gene. EGR-1 has a distinct pattern of expression in the brain, and its induction has been shown to be associated with neuronal activity. Several studies suggest it has a role in neuronal plasticity. EGR-1 has also been found to regulate the expression of synaptobrevin II (a protein important for synaptic exocytosis).
Synonym: EGR-1, Early growth response protein 1, Zif268, zinc finger protein 225, NGFI-A , nerve growth factor-induced protein A,
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Molecular Weight
- 19.9 kDa
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UniProt
- P18146
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Pathways
- Regulation of Carbohydrate Metabolic Process, Regulation of long-term Neuronal Synaptic Plasticity
Target
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