FTH1 Protein
Quick Overview for FTH1 Protein (ABIN7318467)
Target
See all FTH1 ProteinsProtein Type
Origin
Source
Purity
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                                            Purpose
- Recombinant Human FTH Protein
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                                            Sequence
- Met 1-Ser183
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                                            Characteristics
- Recombinant Human Ferritin heavy chain is produced by our E.coli expression system and the target gene encoding Met1-Ser183 is expressed.
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                                            Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
 
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                                            Restrictions
- For Research Use only
 
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                                            Format
- Lyophilized
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                                            Reconstitution
- Please refer to the printed manual for detailed information.
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                                            Buffer
- Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.4.
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                                            Storage
- 4 °C,-20 °C,-80 °C
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                                            Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
 
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    - FTH1 (Ferritin, Heavy Polypeptide 1 (FTH1))
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                                            Alternative Name
- FTH
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                                            Background
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                        Background: Ferritin heavy polypeptide 1(FTH1), is a ubiquitous intracellular protein which stores iron in a soluble, non-toxic, readily available form. FTH1 has ferroxidase activity and is important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. Ferritin is composed of 24 subunits of the light and heavy ferritin chains. It plays a role in delivery of iron to cells and mediates iron uptake in capsule cells of the developing kidney. Variation of ferritin subunit composition may affect iron absorption and release in different tissues. Deficiency of ferritin proteins may cause several neurodegenerative diseases. Almost all living organisms can produce this protein, including algae, bacteria, higher plants, and animals. Synonym: Ferritin heavy chain,FTH1,FTH,FTHL6,Ferritin H subunit,Cell proliferation-inducing gene 15 protein,FHC,HFE5,PIG15 
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                                            Molecular Weight
- 21.2 kDa
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                                            UniProt
- P02794
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                                            Pathways
- Transition Metal Ion Homeostasis
 Target
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