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FTH1 Protein

This Recombinant FTH1 protein is expressed in Escherichia coli (E. coli).
Catalog No. ABIN7318467

Quick Overview for FTH1 Protein (ABIN7318467)

Target

See all FTH1 Proteins
FTH1 (Ferritin, Heavy Polypeptide 1 (FTH1))

Protein Type

Recombinant

Origin

  • 8
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
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Human

Source

  • 10
  • 10
  • 3
  • 2
  • 1
Escherichia coli (E. coli)

Purity

> 95 % as determined by reducing SDS-PAGE.
  • Purpose

    Recombinant Human FTH Protein

    Sequence

    Met 1-Ser183

    Characteristics

    Recombinant Human Ferritin heavy chain is produced by our E.coli expression system and the target gene encoding Met1-Ser183 is expressed.

    Endotoxin Level

    < 1.0 EU per μg as determined by the LAL method.
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  • Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Please refer to the printed manual for detailed information.

    Buffer

    Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.4.

    Storage

    4 °C,-20 °C,-80 °C

    Storage Comment

    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • Target

    FTH1 (Ferritin, Heavy Polypeptide 1 (FTH1))

    Alternative Name

    FTH

    Background

    Background: Ferritin heavy polypeptide 1(FTH1), is a ubiquitous intracellular protein which stores iron in a soluble, non-toxic, readily available form. FTH1 has ferroxidase activity and is important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. Ferritin is composed of 24 subunits of the light and heavy ferritin chains. It plays a role in delivery of iron to cells and mediates iron uptake in capsule cells of the developing kidney. Variation of ferritin subunit composition may affect iron absorption and release in different tissues. Deficiency of ferritin proteins may cause several neurodegenerative diseases. Almost all living organisms can produce this protein, including algae, bacteria, higher plants, and animals.

    Synonym: Ferritin heavy chain,FTH1,FTH,FTHL6,Ferritin H subunit,Cell proliferation-inducing gene 15 protein,FHC,HFE5,PIG15

    Molecular Weight

    21.2 kDa

    UniProt

    P02794

    Pathways

    Transition Metal Ion Homeostasis
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