FGF12 Protein

Catalog No. ABIN7318477

This Recombinant FGF12 protein is produced in Escherichia coli (E. coli).

Quick Overview for FGF12 Protein (ABIN7318477)

Target: FGF12 (Fibroblast Growth Factor 12 (FGF12))

Protein Type: Recombinant

Origin: Human

Source: Escherichia coli (E. coli)

Purity: > 95 % as determined by reducing SDS-PAGE.

Product Details

Purpose: Recombinant Human FGF-12/FGF12 Protein

Sequence: Met 1-Thr181

Characteristics: Recombinant Human Fibroblast Growth Factor 12 is produced by our E.coli expression system and the target gene encoding Met1-Thr181 is expressed.

Sterility: 0.2 μm filtered

Endotoxin Level: < 1.0 EU per μg of the protein as determined by the LAL method.

Biological Activity Comment: Not validated for activity

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: Lyophilized from a 0.2 μm filtered solution of PBS, 5 mM EDTA, pH 7.5.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween 80 are added as protectants before lyophilization.

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Expiry Date: 12 months

Target Details

Target: FGF12 (Fibroblast Growth Factor 12 (FGF12))

Alternative Name: FGF-12/FGF12

Background: FGF-12,FGF12,FGF12B,FHF-1,FHF1,Fibroblast Growth Factor 12,Fibroblast Growth Factor Homologous Factor 1,Myocyte-Activating Factor,Fibroblast Growth Factor 12 (FGF-12) is a member of the fibroblast growth factor (FGF) family. FGF-12 is probably involved in nervous system development and function. FGF-12 lacks the N-terminal signal sequence present in most of the FGF family members, but it contains clusters of basic residues that have been demonstrated to act as a nuclear localization signal. When transfectedinto mammalian cells, this protein accumulated in the nucleus, but was not secreted. The specific function of this gene has not yet been determined. Two alternatively spliced transcript variants encoding distinct isoforms have been reported.

Molecular Weight:

Calculated MW: 20.5 kDa

Observed MW: 19 kDa

Gene ID: 2257

UniProt: P61328

Pathways: Negative Regulation of Transporter Activity