GABARAPL1 Protein (His tag)

Catalog No. ABIN7318509

Recombinant GABARAPL1 protein expressed in Escherichia coli (E. coli).

Quick Overview for GABARAPL1 Protein (His tag) (ABIN7318509)

Target: GABARAPL1 (GABA(A) Receptor-Associated Protein Like 1 (GABARAPL1))

Protein Type: Recombinant

Origin: Human

Source: Escherichia coli (E. coli)

Purity: > 95 % as determined by reducing SDS-PAGE.

Product Details

Purification tag / Conjugate: This GABARAPL1 protein is labelled with His tag.

Purpose: Recombinant Human GABARAPL1 Protein (His Tag)

Sequence: Met 1-Lys117

Characteristics: Recombinant Human gamma-Aminobutyric Acid Receptor-Associated Protein-Like 1 is produced by our E.coli expression system and the target gene encoding Met1-Lys117 is expressed with a 6His tag at the N-terminus.

Sterility: 0.2 μm filtered

Endotoxin Level: < 1.0 EU per μg of the protein as determined by the LAL method.

Biological Activity Comment: Not validated for activity

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.2.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween 80 are added as protectants before lyophilization.

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Expiry Date: 12 months

Target Details

Target: GABARAPL1 (GABA(A) Receptor-Associated Protein Like 1 (GABARAPL1))

Alternative Name: GABARAPL1

Background: Early Estrogen-Regulated Protein,GABA(A) Receptor-Associated Protein-Like 1,GABARAPL1,GEC-1,GEC1,Gamma-Aminobutyric Acid Receptor-Associated Protein-Like 1,Glandular Epithelial Cell Protein 1,Gamma-Aminobutyric Acid Receptor-Associated Protein-Like 1 (GABARAPL1) is a cytoplasmic protein that belongs to the MAP1 LC3 family. GABARAPL1 is expressed at very high levels in the brain, heart, peripheral blood leukocytes, liver, kidney, placenta, and skeletal muscle. It can interact with GABRG2, OPRK1 and β-Tubulin. GABARAPL1 increases cell-surface expression of kappa-type opioid receptor through facilitating anterograde intracellular trafficking of the receptor.

Molecular Weight:

Calculated MW: 16.2 kDa

Observed MW: 20 kDa

Gene ID: 23710

UniProt: Q9H0R8

Pathways: Autophagy