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GALK1 Protein (His tag)

This Recombinant GALK1 protein is expressed in Escherichia coli (E. coli).
Catalog No. ABIN7319607

Quick Overview for GALK1 Protein (His tag) (ABIN7319607)

Target

See all GALK1 Proteins
GALK1 (Galactokinase 1 (GALK1))

Protein Type

Recombinant

Origin

  • 7
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Human

Source

  • 40
  • 3
  • 2
  • 2
  • 1
  • 1
Escherichia coli (E. coli)

Purity

> 85 % as determined by reducing SDS-PAGE.
  • Purification tag / Conjugate

    This GALK1 protein is labelled with His tag.

    Purpose

    Recombinant Human GALK1/Galactokinase Protein (His Tag)

    Sequence

    Met1-Leu392

    Characteristics

    Recombinant Human GALK1 is produced by our E.coli expression system and the target gene encoding Met1-Leu392 is expressed with a 6His tag at the C-terminus.

    Endotoxin Level

    < 1.0 EU per μg as determined by the LAL method.
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    Product
    Expression System
    Conjugate
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    Expression System HEK-293 Cells
    Conjugate His tag
    Origin Human
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  • Restrictions

    For Research Use only
  • Format

    Frozen, Liquid

    Buffer

    Supplied as a 0.2 μm filtered solution of 20 mM TrisHCl, 150 mM NaCl, pH 8.0.

    Storage

    -20 °C

    Storage Comment

    Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
  • Target

    GALK1 (Galactokinase 1 (GALK1))

    Alternative Name

    GALK1/Galactokinase

    Background

    Background: Galactokinase belongs to the GHMP kinase family and GalK subfamily. Galactokinase is more important to the galactose metabolism pathway. It modifies galactose to create a similar molecule called Galactose-1-Phosphate.Thus, a series of additional steps converts Galactose-1-Phosphate to another simple sugar Glucose, which is the main energy source for most cells. Galactokinase deficiency results in Galactosemia II, an autosomal recessive deficiency characterized by congenital cataracts during infancy and presenile cataracts in the adult population. The cataracts are secondary to accumulation of Galactitol in the lenses.

    Synonym: Galactokinase, Galactose Kinase, GALK1, GALK

    Molecular Weight

    43.3 kDa

    UniProt

    P51570
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