GALK1 Protein (AA 1-392) (His tag)

Catalog No. ABIN1096708

Product Details

Target: GALK1 (Galactokinase 1 (GALK1))

Protein Type: Recombinant

Protein Characteristics: AA 1-392

Origin: Human

Source: Escherichia coli (E. coli)

Purification tag / Conjugate: This GALK1 protein is labelled with His tag.

Purpose: Recombinant Human Galactokinase/GALK1 (C-6His)

Sequence: MAALRQPQVA ELLAEARRAF REEFGAEPEL AVSAPGRVNL IGEHTDYNQG LVLPMALELM TVLVGSPRKD GLVSLLTTSE GADEPQRLQF PLPTAQRSLE PGTPRWANYV KGVIQYYPAA PLPGFSAVVV SSVPLGGGLS SSASLEVATY TFLQQLCPDS GTIAARAQVC QQAEHSFAGM PCGIMDQFIS LMGQKGHALL IDCRSLETSL VPLSDPKLAV LITNSNVRHS LASSEYPVRR RQCEEVARAL GKESLREVQL EELEAARDLV SKEGFRRARH VVGEIRRTAQ AAAALRRGDY RAFGRLMVES HRSLRDDYEV SCPELDQLVE AALAVPGVYG SRMTGGGFGG CTVTLLEASA APHAMRHIQE HYGGTATFYL SQAADGAKVL CLLEHHHHHH

Characteristics: Recombinant Human Galactokinase/GALK1 is produced by our E. coli expression system. The target protein is expressed with sequence (Met1-Leu392) of Human GALK1 fused with a 6His tag at the C-terminus.

Purity: > 95 % as determined by reducing SDS-PAGE.

Sterility: 0.2 μm filtered

Endotoxin Level: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Reconstitution: It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Buffer: Supplied as a 0.2 μm filtered solution of 20 mM TrisHCl, 150 mM NaCl, pH 8.0.

Handling Advice: Always centrifuge tubes before opening. Do not mix by vortex or pipetting.

Storage: -80 °C

Storage Comment: Store at < -20°C, stable for 6 months after receipt.
Please minimize freeze-thaw cycles.

Expiry Date: 6 months

Target Details

Target: GALK1 (Galactokinase 1 (GALK1))

Alternative Name: Galactokinase (GALK1 Products)

Synonyms: GALK Protein, GK1 Protein, AA409894 Protein, Gk Protein, Glk Protein, Glk1 Protein, Galk Protein, galactokinase 1 Protein, GALK1 Protein, Galk1 Protein

Sub Type: Fusionprotein

Background: Galactokinase belongs to the GHMP kinase family and GalK subfamily. Galactokinase is more important to the galactose metabolism pathway. It modifies galactose to create a similar molecule called Galactose-1-Phosphate.Thus, a series of additional steps converts Galactose-1-Phosphate to another simple sugar Glucose, which is the main energy source for most cells. Galactokinase deficiency results in Galactosemia II, an autosomal recessive deficiency characterized by congenital cataracts during infancy and presenile cataracts in the adult population. The cataracts are secondary to accumulation of Galactitol in the lenses.
Alternative Names: Galactokinase, Galactose Kinase, GALK1, GALK

Molecular Weight: 43.3 kDa

UniProt: P51570