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CXCL9 Protein

CXCL9 Origin: Mouse Host: Escherichia coli (E. coli) Recombinant > 95 % as determined by SDS-PAGE
Catalog No. ABIN7320505
  • Target See all CXCL9 Proteins
    CXCL9 (gamma-Interferon-Induced Monokine (CXCL9))
    Protein Type
    Recombinant
    Origin
    • 9
    • 4
    • 2
    • 1
    Mouse
    Source
    • 8
    • 4
    • 1
    • 1
    • 1
    Escherichia coli (E. coli)
    Purpose
    Recombinant Mouse CXCL9 Protein
    Sequence
    Thr22-Thr126
    Characteristics
    Recombinant Mouse C-X-C Motif Chemokine 9 is produced by our E.coli expression system and the target gene encoding Thr22-Thr126 is expressed.
    Purity
    > 95 % as determined by SDS-PAGE
    Endotoxin Level
    < 1.0 EU per μg as determined by the LAL method.
    Top Product
    Discover our top product CXCL9 Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Please refer to the printed manual for detailed information.
    Buffer
    Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
    Storage
    4 °C,-20 °C,-80 °C
    Storage Comment
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • Target
    CXCL9 (gamma-Interferon-Induced Monokine (CXCL9))
    Alternative Name
    CXCL9 (CXCL9 Products)
    Synonyms
    CMK Protein, Humig Protein, MIG Protein, SCYB9 Protein, crg-10 Protein, BB139920 Protein, Mig Protein, MuMIG Protein, Scyb9 Protein, C-X-C motif chemokine ligand 9 Protein, chemokine (C-X-C motif) ligand 9 Protein, CXCL9 Protein, Cxcl9 Protein
    Background

    Background: Chemokine (C-X-C motif) ligand 9 (CXCL9, MIG), is a small cytokine belonging to the CXC chemokine family. CXCL9 functions as one of the three ligands of chemokine receptor CXCR3 which is a G protein-coupled receptor found predominantly on T cells. It together with CXCL10 and CXCL11, may activate CXCR3 by binding to it. CXCL9 serves as a cytokine that affects the growth, movement, or activation state of cells that participate in immune and inflammatory response. It has been observed that tumour endothelial cells secrete high levels of CXCL9 in all, and CXCL10 in most melanoma metastases. it plays an important role in CD4+ T lymphocyte recruitment and development of CAV, MOMA-2+ macrophages are the predominant recipient-derived source of CXCL9, and recipient CD4 lymphocytes are necessary for sustained CXCL9 production and CAV development in this model.

    Synonym: C-X-C motif chemokine 9,Cxcl9,Gamma-interferon-induced monokine,Monokine induced by interferon-gamma,MIG,Small-inducible cytokine B9,Scyb9

    Molecular Weight
    12.3 kDa
    UniProt
    P18340
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