GLIPR1 Protein (His tag)

Catalog No. ABIN7319346

This Recombinant GLIPR1 protein is expressed in Human Cells.

Quick Overview for GLIPR1 Protein (His tag) (ABIN7319346)

Target: GLIPR1 (GLI Pathogenesis-Related 1 (GLIPR1))

Protein Type: Recombinant

Origin: Human

Source: Human Cells

Purity: > 95 % as determined by reducing SDS-PAGE.

Product Details

Purification tag / Conjugate: This GLIPR1 protein is labelled with His tag.

Purpose: Recombinant Human GLIPR1 Protein (His Tag)

Sequence: Asn22-Arg232

Characteristics: Recombinant Human Glioma Pathogenesis-Related Protein 1 is produced by our Mammalian expression system and the target gene encoding Asn22-Arg232 is expressed with a 6His tag at the C-terminus.

Endotoxin Level: < 1.0 EU per μg as determined by the LAL method.

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.4.

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Target Details

Target: GLIPR1 (GLI Pathogenesis-Related 1 (GLIPR1))

Alternative Name: GLIPR1

Background:

Background: Glioma Pathogenesis-Related Protein 1 (GLIPR1) is a member of the CRISP family. It is a single-pass membrane protein with 266 amino acids. GLIPR1 is highly expressed in the lung and kidney and lowly expressed in the heart and liver. It is also highly expressed in cell lines that are derived from nervous system tumors arising from glia, conversely, it is lowly expressed in non-glial-derived nervous system tumor cell lines. GLIPR1 is only expressed in brain tumor glioblastoma multiforme/astrocytoma and not expressed in other nervous system tumors nor normal adult or fetal tissues.

Synonym: Glioma Pathogenesis-Related Protein 1, GliPR 1, Protein RTVP-1, GLIPR1, GLIPR, RTVP1

Molecular Weight: 25.2 kDa

NCBI Accession: NP_006842

Pathways: Regulation of Lipid Metabolism by PPARalpha