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Grancalcin Protein

This Recombinant Grancalcin protein is expressed in Escherichia coli (E. coli).
Catalog No. ABIN7318548
$345.12
Plus shipping costs $50.00
Shipping to: United States
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Quick Overview for Grancalcin Protein (ABIN7318548)

Target

See all Grancalcin (GCA) Proteins
Grancalcin (GCA) (Grancalcin, EF-Hand Calcium Binding Protein (GCA))

Protein Type

Recombinant

Origin

  • 13
  • 3
Human

Source

  • 8
  • 4
  • 2
  • 1
  • 1
Escherichia coli (E. coli)

Purity

> 95 % as determined by reducing SDS-PAGE.
  • Purpose

    Recombinant Human Grancalcin/GCA Protein

    Sequence

    Met 1-Ile217

    Characteristics

    Recombinant Human Grancalcin is produced by our E.coli expression system and the target gene encoding Met1-Ile217 is expressed.

    Endotoxin Level

    < 1.0 EU per μg as determined by the LAL method.
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  • Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Please refer to the printed manual for detailed information.

    Buffer

    Lyophilized from a 0.2 μm filtered solution of 20 mM TrisHCl, 150 mM NaCl, 1 mM EDTA, pH 8.5.

    Storage

    4 °C,-20 °C,-80 °C

    Storage Comment

    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • Target

    Grancalcin (GCA) (Grancalcin, EF-Hand Calcium Binding Protein (GCA))

    Alternative Name

    Grancalcin/GCA

    Background

    Background: Grancalcin (GCA) is a cytoplasmic granule membrane protein that contains 4 EF-hand domains. GCA is calcium-binding protein and particularly abundant in human neutrophils. GCA is highly expressed in bone marrow, and it can be detected in neutrophils and macrophages. Calcium-binding protein GCA cooperates with SRI and LCP1, so it may play a role in the adhesion of neutrophils to fibronectin. GCA also may play a role in the formation of focal adhesions.

    Synonym: Grancalcin, GCA, GCL

    Molecular Weight

    24.0 kDa

    UniProt

    P28676
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