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Grancalcin Protein

This Recombinant Grancalcin protein is expressed in Escherichia coli (E. coli).
Catalog No. ABIN7318548

Quick Overview for Grancalcin Protein (ABIN7318548)

Target

See all Grancalcin (GCA) Proteins
Grancalcin (GCA) (Grancalcin, EF-Hand Calcium Binding Protein (GCA))

Protein Type

Recombinant

Origin

  • 12
  • 3
Human

Source

  • 8
  • 4
  • 2
  • 1
Escherichia coli (E. coli)

Purity

> 95 % as determined by reducing SDS-PAGE.
  • Purpose

    Recombinant Human Grancalcin/GCA Protein

    Sequence

    Met 1-Ile217

    Characteristics

    Recombinant Human Grancalcin is produced by our E.coli expression system and the target gene encoding Met1-Ile217 is expressed.

    Endotoxin Level

    < 1.0 EU per μg as determined by the LAL method.
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  • Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Please refer to the printed manual for detailed information.

    Buffer

    Lyophilized from a 0.2 μm filtered solution of 20 mM TrisHCl, 150 mM NaCl, 1 mM EDTA, pH 8.5.

    Storage

    4 °C,-20 °C,-80 °C

    Storage Comment

    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • Target

    Grancalcin (GCA) (Grancalcin, EF-Hand Calcium Binding Protein (GCA))

    Alternative Name

    Grancalcin/GCA

    Background

    Background: Grancalcin (GCA) is a cytoplasmic granule membrane protein that contains 4 EF-hand domains. GCA is calcium-binding protein and particularly abundant in human neutrophils. GCA is highly expressed in bone marrow, and it can be detected in neutrophils and macrophages. Calcium-binding protein GCA cooperates with SRI and LCP1, so it may play a role in the adhesion of neutrophils to fibronectin. GCA also may play a role in the formation of focal adhesions.

    Synonym: Grancalcin, GCA, GCL

    Molecular Weight

    24.0 kDa

    UniProt

    P28676
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