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Grancalcin Protein

GCA Origin: Human Host: Escherichia coli (E. coli) Recombinant > 95 % as determined by reducing SDS-PAGE.
Catalog No. ABIN7318548
  • Target See all Grancalcin (GCA) Proteins
    Grancalcin (GCA) (Grancalcin, EF-Hand Calcium Binding Protein (GCA))
    Protein Type
    Recombinant
    Origin
    • 8
    • 2
    Human
    Source
    • 7
    • 1
    • 1
    • 1
    Escherichia coli (E. coli)
    Purpose
    Recombinant Human Grancalcin/GCA Protein
    Sequence
    Met 1-Ile217
    Characteristics
    Recombinant Human Grancalcin is produced by our E.coli expression system and the target gene encoding Met1-Ile217 is expressed.
    Purity
    > 95 % as determined by reducing SDS-PAGE.
    Endotoxin Level
    < 1.0 EU per μg as determined by the LAL method.
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    Discover our top product GCA Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Please refer to the printed manual for detailed information.
    Buffer
    Lyophilized from a 0.2 μm filtered solution of 20 mM TrisHCl, 150 mM NaCl, 1 mM EDTA, pH 8.5.
    Storage
    4 °C,-20 °C,-80 °C
    Storage Comment
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • Target
    Grancalcin (GCA) (Grancalcin, EF-Hand Calcium Binding Protein (GCA))
    Alternative Name
    Grancalcin/GCA (GCA Products)
    Synonyms
    Grancalcin Protein, 5133401E04Rik Protein, AI573844 Protein, GCL Protein, zgc:92027 Protein, grancalcin Protein, Grancalcin Protein, zgc:92027 Protein, GCA Protein, gran Protein, LOC100280890 Protein, Gca Protein
    Background

    Background: Grancalcin (GCA) is a cytoplasmic granule membrane protein that contains 4 EF-hand domains. GCA is calcium-binding protein and particularly abundant in human neutrophils. GCA is highly expressed in bone marrow, and it can be detected in neutrophils and macrophages. Calcium-binding protein GCA cooperates with SRI and LCP1, so it may play a role in the adhesion of neutrophils to fibronectin. GCA also may play a role in the formation of focal adhesions.

    Synonym: Grancalcin, GCA, GCL

    Molecular Weight
    24.0 kDa
    UniProt
    P28676
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