Catalog No. ABIN7321258
-20% for 20 Years of ABO
$174.28
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Quick Overview for IgG2a Fc (AA 98-322) Protein (ABIN7321258)
Target
IgG2a Fc
Protein Type
Recombinant
Origin
Rat
Source
HEK-293 Cells
Purity
> 95 % as determined by reducing SDS-PAGE.
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Protein Characteristics
- AA 98-322
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Purpose
- Recombinant Rat IgG2A Fc/Igg-2a Protein
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Sequence
- Val98-Lys322
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Characteristics
- Recombinant Rat Immunoglobulin G2A Fc is produced by our Mammalian expression system and the target gene encoding Val98-Lys322 is expressed.
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Sterility
- 0.2 μm filtered
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Endotoxin Level
- < 1.0 EU per μg of the protein as determined by the LAL method.
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Biological Activity Comment
- Not validated for activity
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IgG2a Fc (AA 98-330) (Active) protein
Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
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Lyophilized from a 0.2 μm filtered solution of 20 mM Tris-HCl, pH 8.5.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween 80 are added as protectants before lyophilization. -
Storage
- 4 °C,-20 °C,-80 °C
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Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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Expiry Date
- 12 months
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- IgG2a Fc
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Alternative Name
- IgG2A Fc/Igg-2a
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Background
- Ig gamma-2A chain C region,Igg-2a,Immunoglobulin G (IgG) is a type of antibody composed of four peptide chains-two identical heavy chains and two identical light chains arranged in a Y-shape typical of antibody monomers.There are four IgG subclasses (IgG1, 2, 3, and 4) in humans, named in order of their abundance in serum. The IgG2a isotype was able to interact very efficiently with FcgammaR, and share approximately 64-78 % amino acid sequence identity with IgG1 and IgG2b in the heavy chain constant region domains, CH1, CH2 and CH3, which cause the diffrence in the interaction with complement, NK and mast cells, induction or inhibition by specific cytokines, and ability to cross the placenta.
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Molecular Weight
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Calculated MW: 35.2 kDa
Observed MW: 30-35 kDa
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UniProt
- P20760
Target
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