IP6K1 Protein (His-GST)
Quick Overview for IP6K1 Protein (His-GST) (ABIN7196191)
Target
See all IP6K1 ProteinsProtein Type
Origin
Source
Purity
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Purification tag / Conjugate
- This IP6K1 protein is labelled with His-GST.
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Purpose
- Recombinant Human IHPK1 Protein (His & GST Tag)
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Sequence
- Met 1-Gln 441
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Characteristics
- A DNA sequence encoding the human IHPK1 (Q92551-1) (Met1-Gln441) was fused with the N-terminal polyhistidine-tagged GST tag at the N-terminus.
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Sterility
- 0.2 μm filtered
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Endotoxin Level
- < 1.0 EU per μg of the protein as determined by the LAL method.
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Biological Activity Comment
- Not validated for activity
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Inositol Hexakisphosphate Kinase 1 (IP6K1) (AA 182-275) protein (GST tag)
IP6K1 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Inositol Hexakisphosphate Kinase 1 (IP6K1) (AA 1-441) protein (His tag)IP6K1 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Supplied as sterile solution of 20 mM Tris, 500 mM NaCl, pH 8.0, 10 % glycerol
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Storage
- -20 °C
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Storage Comment
- Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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Expiry Date
- 6 months
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- IP6K1 (Inositol Hexakisphosphate Kinase 1 (IP6K1))
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Alternative Name
- IHPK1
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Background
- IHPK1,PiUS,IHPK1 is a inositol hexaphosphate kinase (IHPK) protein which belongs to the inositol phosphokinase (IPK) family. IHPK proteins are likely responsible for the conversion of inositol hexakisphosphate (InsP6) to diphosphoinositol pentakisphosphate (InsP7/PP-InsP5). IHPK1 may also convert 1,3,4,5,6-pentakisphosphate (InsP5) to PP-InsP4 and affect the growth suppressive and apoptotic activities of interferon-beta in some ovarian cancers. During cell death, IHPK1 activity is enhanced, and intracellular InsP7 level is augmented. The distribution of IHPK1 or another predisposing gene affected by position effect of translocation may explain the T2DM phenotype at least in this family.
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Molecular Weight
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Calculated MW: 78.0 kDa
Observed MW: 88 kDa
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Gene ID
- 9807
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UniProt
- Q92551
Target
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