ICAM2 Protein (Fc Tag)

Catalog No. ABIN7320710

Recombinant ICAM2 protein expressed in Human Cells.

Quick Overview for ICAM2 Protein (Fc Tag) (ABIN7320710)

Target: ICAM2 (Intercellular Adhesion Molecule 2 (ICAM2))

Protein Type: Recombinant

Origin: Mouse

Source: Human Cells

Purity: > 95 % as determined by SDS-PAGE

Product Details

Purification tag / Conjugate: This ICAM2 protein is labelled with Fc Tag.

Purpose: Recombinant Mouse ICAM-2/CD102 Protein (Fc Tag)

Sequence: Lys23-Gln222

Characteristics: Recombinant Mouse Intercellular adhesion molecule 2 is produced by our Mammalian expression system and the target gene encoding Lys23-Gln222 is expressed with a Fc tag at the C-terminus.

Endotoxin Level: < 1.0 EU per μg as determined by the LAL method.

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from a 0.2 μm filtered solution of 20 mM Tris,150 mM NaCl, pH 8.0.

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Target Details

Target: ICAM2 (Intercellular Adhesion Molecule 2 (ICAM2))

Alternative Name: ICAM-2/CD102

Background:

Background: ICAM-2 is a 55-65 kD transmembrane glycoprotein possessing 2 extracellular Ig domains, a single transmembrane domain, and a short 26-amino acid cytoplasmic domain. ICAM-2 is expressed on most leukocytes, and is strongly expressed on vascular endothelial cells. Interactions of ICAM-2 and the integrin receptors mediate cell adhesion in a wide range of lymphocyte, monocyte, natural killer cell, and granulocytewith other cells, and play important roles in many adhesion-dependent immune and inflammation responses, such as T cell aggregation, NK-cell cytotoxicity and migration, lymphocyte recirculation, etc. Serum levels of ICAM-2 correlated significantly with the inflammatory and course sequences of trichinosis in mice and had a similar relation with blood eosinophilia. So, estimation of ICAM-2 serum levels may prove useful in diagnosis of trichinosis recent infections, and in monitoring the prognosis and response to treatment.

Synonym: Intercellular adhesion molecule 2, Icam2, ICAM-2, Lymphocyte function-associated AG-1 counter-receptor, CD102, Icam-2, CD102 antigen,Ly-60

Molecular Weight: 49.7 kDa

NCBI Accession: NP_034624