IL13 Receptor alpha 1 Protein (His tag,AVI tag)

Catalog No. ABIN7320865

This Recombinant IL13 Receptor alpha 1 protein is produced in Human Cells.

Quick Overview for IL13 Receptor alpha 1 Protein (His tag,AVI tag) (ABIN7320865)

Target: IL13 Receptor alpha 1 (IL13RA1) (Interleukin 13 Receptor, alpha 1 (IL13RA1))

Protein Type: Recombinant

Origin: Mouse

Source: Human Cells

Purity: > 95 % as determined by reducing SDS-PAGE.

Product Details

Purification tag / Conjugate: This IL13 Receptor alpha 1 protein is labelled with His tag,AVI tag.

Purpose: Recombinant Mouse IL13RA1 Protein (AVI & His Tag)

Sequence: Ala25-Thr340

Characteristics: Biotinylated Recombinant Mouse IL-13RA is produced by ourMammalian expression system and the target gene encoding Ala25-Thr340 is expressed with a Avi, 6Histag at the C-terminus.

Endotoxin Level: < 1.0 EU per μg as determined by the LAL method.

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Target Details

Target: IL13 Receptor alpha 1 (IL13RA1) (Interleukin 13 Receptor, alpha 1 (IL13RA1))

Alternative Name: IL13RA1

Background:

Background: Interleukin-13 receptor subunit alpha-1(IL-13RA1), also known as NR4, belongs to the hemopoietin receptor family. Interleukin-13 receptor is a complex of IL4R, IL13RA1, and possibly other components. It interacts with TRAF3IP1 and binds with low affinity to interleukin-13(IL3). IL-13RA1, together with IL4RA, can form a functional receptor for IL13. It also serves as an alternate accessory protein to the common cytokine receptor gamma chain for interleukin-4 (IL4) signaling, but cannot replace the function of IL2RG in allowing enhanced interleukin-2 (IL2) binding activity. The WSXWS motif in domains appears to be necessary for proper protein folding and thereby efficient intracellular transport and cell-surface receptor binding.

Synonym: Interleukin-13 receptor subunit alpha-1,IL-13RA1,Interleukin-13-binding protein,Novel cytokine receptor 4,NR4,CD213a1, IL-13 R alpha 1

Molecular Weight: 38.7 kDa

UniProt: O09030

Pathways: JAK-STAT Signaling, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response