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IL17F Protein

Recombinant IL17F protein expressed in Human Cells.
Catalog No. ABIN7318652

Quick Overview for IL17F Protein (ABIN7318652)

Target

See all IL17F Proteins
IL17F (Interleukin 17F (IL17F))

Protein Type

Recombinant

Origin

  • 15
  • 8
  • 5
  • 2
  • 1
Human

Source

  • 13
  • 9
  • 3
  • 2
  • 2
  • 1
  • 1
Human Cells

Purity

> 95 % as determined by reducing SDS-PAGE.
  • Purpose

    Recombinant Human Interleukin-17F/IL-17F Protein

    Sequence

    Arg31-Gln163

    Characteristics

    Recombinant Human Interleukin-17F is produced by our Mammalian expression system and the target gene encoding Arg31-Gln163 is expressed.

    Endotoxin Level

    < 1.0 EU per μg as determined by the LAL method.
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  • Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Please refer to the printed manual for detailed information.

    Buffer

    Lyophilized from a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.4.

    Storage

    4 °C,-20 °C,-80 °C

    Storage Comment

    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • Target

    IL17F (Interleukin 17F (IL17F))

    Alternative Name

    Interleukin-17F/IL-17F

    Background

    Background: Interleukin-17F (IL-17F) exists in a disulfide-linked heterodimer that belongs to the IL-17 family. IL-17F is expressed in activated, but not resting, CD4+ T-cells and activated monocytes. IL-17F has been shown to stimulate the production of several other cytokines, including IL-6, IL-8, and granulocyte colony-stimulating factor. IL-17F can regulate cartilage matrix turnover and stimulates PBMC and T-cell proliferation. IL-17F is also found to inhibit the angiogenesis of endothelial cells and induce endothelial cells to produce IL2, TGFB1/TGFB, and monocyte chemoattractant protein-1. Defects in IL-17F are the cause of familial candidiasis type 6 (CANDF6).

    Synonym: Interleukin-17F, IL-17F, Cytokine ML-1, Interleukin-24, IL-24, IL17F, IL24

    Molecular Weight

    14.9 kDa

    UniProt

    Q96PD4

    Pathways

    Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Endopeptidase Activity
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