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Kallikrein 1 Protein (KLK1) (His tag)

KLK1 Origin: Mouse Host: HEK-293 Cells Recombinant > 90 % as determined by SDS-PAGE Active
Catalog No. ABIN7196656
  • Target See all Kallikrein 1 (KLK1) Proteins
    Kallikrein 1 (KLK1)
    Protein Type
    Recombinant
    Biological Activity
    Active
    Origin
    • 12
    • 5
    • 3
    • 1
    Mouse
    Source
    • 7
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This Kallikrein 1 protein is labelled with His tag.
    Purpose
    Recombinant Mouse Kallikrein 1/KLK1 Protein (His Tag)(Active)
    Sequence
    Met1-Asp261
    Characteristics
    A DNA sequence encoding the mouse KLK1 (P15947) (Met1-Asp261) was expressed with a C-terminal polyhistidine tag.
    Purity
    > 90 % as determined by SDS-PAGE
    Endotoxin Level
    < 1.0 EU per μg of the protein as determined by the LAL method.
    Biological Activity Comment
    Measured by its ability to cleave a flourogenic peptide substrate Pro-Phe-Arg-7-amido-4-methylcoumarin(PFR-AMC).The specific activity is >6, 000 pmol/min/μg.(Activation description: The proenzyme needs to be activated by Thermolysin for an activated form)
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    Discover our top product KLK1 Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Please refer to the printed manual for detailed information.
    Buffer
    Lyophilized from sterile 25  mM Tris, 5  mM CaCl2, 0.15 M NaCl,  pH 7.4
    Storage
    4 °C,-20 °C,-80 °C
    Storage Comment
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • Target
    Kallikrein 1 (KLK1)
    Alternative Name
    Kallikrein 1/KLK1 (KLK1 Products)
    Synonyms
    KLKR Protein, Klk6 Protein, hK1 Protein, klkr Protein, kallikrein Protein, 0610007D04Rik Protein, Kal Protein, Klk1b6 Protein, mGk-6 Protein, kallikrein 1 Protein, kallikrein 1 L homeolog Protein, KLK1 Protein, klk1.L Protein, LOC100101620 Protein, Klk1 Protein
    Background

    Background: Human tissue kallikrein (KLK1) is a serine protease, component of the KKS that has been demonstrated to exert pleiotropic beneficial effects in protection from tissue injury through its antiinflammatory, antiapoptotic, antifibrotic and antioxidative actions.Polymorphism of the human tissue kallikrein 1 (KLK1) A1789G gene is associated with susceptibility to hypertension.

    Synonym: Glandular kallikrein K1, KAL-B, Renal kallikrein, Tissue kallikrein-6, mGK-6

    Molecular Weight
    28.3 kDa
    UniProt
    P15947
    Pathways
    Complement System
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