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Kallikrein 1 Protein (KLK1) (His tag)

KLK1 Origin: Mouse Host: Human Cells Recombinant > 95 % as determined by reducing SDS-PAGE.
Catalog No. ABIN7320811
  • Target See all Kallikrein 1 (KLK1) Proteins
    Kallikrein 1 (KLK1)
    Protein Type
    Recombinant
    Origin
    • 12
    • 5
    • 3
    • 1
    Mouse
    Source
    • 7
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    Human Cells
    Purification tag / Conjugate
    This Kallikrein 1 protein is labelled with His tag.
    Purpose
    Recombinant Mouse Kallikrein 1/KLK1 Protein (His Tag)
    Sequence
    Pro19-Asp261
    Characteristics
    Recombinant Mouse Kallikrein-1 is produced by our Mammalian expression system and the target gene encoding Pro19-Asp261 is expressed with a 6His tag at the C-terminus.
    Purity
    > 95 % as determined by reducing SDS-PAGE.
    Endotoxin Level
    < 1.0 EU per μg as determined by the LAL method.
    Top Product
    Discover our top product KLK1 Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Please refer to the printed manual for detailed information.
    Buffer
    Lyophilized from a 0.2 μm filtered solution of 20 mM Tris,150 mM NaCl, pH 7.5.
    Storage
    4 °C,-20 °C,-80 °C
    Storage Comment
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • Target
    Kallikrein 1 (KLK1)
    Alternative Name
    Kallikrein 1/KLK1 (KLK1 Products)
    Synonyms
    KLKR Protein, Klk6 Protein, hK1 Protein, klkr Protein, kallikrein Protein, 0610007D04Rik Protein, Kal Protein, Klk1b6 Protein, mGk-6 Protein, kallikrein 1 Protein, kallikrein 1 L homeolog Protein, KLK1 Protein, klk1.L Protein, LOC100101620 Protein, Klk1 Protein
    Background

    Background: Kallikreins belongs to the family of trypsin-like serine proteases, many of which are associated with a variety of cancers. Kallikrein 1 (KLK1) is also known as tissue kallikrein and urinary kallikrein. KLK1 is synthesized as a 261 amino acid (aa) protein that contains a 18 aa signal peptide and a 241 aa proprotein. An important physiological function of KLK1 cleaves Met-Lys and Arg-Ser bonds in kininogen to release Lys-bradykinin. Kinins regulate vasodilation, blood pressure reduction, smooth muscle relaxation and contraction, pain induction and inflammation.

    Synonym: Glandular kallikrein K1, KAL-B, Renal kallikrein, Tissue kallikrein-6, mGK-6

    Molecular Weight
    27.9 kDa
    UniProt
    P15947
    Pathways
    Complement System
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