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Kallikrein 1 Protein (KLK1) (His tag)

Recombinant Kallikrein 1 protein expressed in Human Cells.
Catalog No. ABIN7320811

Quick Overview for Kallikrein 1 Protein (KLK1) (His tag) (ABIN7320811)

Target

See all Kallikrein 1 (KLK1) Proteins
Kallikrein 1 (KLK1)

Protein Type

Recombinant

Origin

  • 12
  • 4
  • 3
  • 1
  • 1
Mouse

Source

  • 9
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
Human Cells

Purity

> 95 % as determined by reducing SDS-PAGE.
  • Purification tag / Conjugate

    This Kallikrein 1 protein is labelled with His tag.

    Purpose

    Recombinant Mouse Kallikrein 1/KLK1 Protein (His Tag)

    Sequence

    Pro19-Asp261

    Characteristics

    Recombinant Mouse Kallikrein-1 is produced by our Mammalian expression system and the target gene encoding Pro19-Asp261 is expressed with a 6His tag at the C-terminus.

    Endotoxin Level

    < 1.0 EU per μg as determined by the LAL method.
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  • Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Please refer to the printed manual for detailed information.

    Buffer

    Lyophilized from a 0.2 μm filtered solution of 20 mM Tris,150 mM NaCl, pH 7.5.

    Storage

    4 °C,-20 °C,-80 °C

    Storage Comment

    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • Target

    Kallikrein 1 (KLK1)

    Alternative Name

    Kallikrein 1/KLK1

    Background

    Background: Kallikreins belongs to the family of trypsin-like serine proteases, many of which are associated with a variety of cancers. Kallikrein 1 (KLK1) is also known as tissue kallikrein and urinary kallikrein. KLK1 is synthesized as a 261 amino acid (aa) protein that contains a 18 aa signal peptide and a 241 aa proprotein. An important physiological function of KLK1 cleaves Met-Lys and Arg-Ser bonds in kininogen to release Lys-bradykinin. Kinins regulate vasodilation, blood pressure reduction, smooth muscle relaxation and contraction, pain induction and inflammation.

    Synonym: Glandular kallikrein K1, KAL-B, Renal kallikrein, Tissue kallikrein-6, mGK-6

    Molecular Weight

    27.9 kDa

    UniProt

    P15947

    Pathways

    Complement System
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