Kallikrein 1 Protein (KLK1) (His tag)
Quick Overview for Kallikrein 1 Protein (KLK1) (His tag) (ABIN7320811)
Target
See all Kallikrein 1 (KLK1) ProteinsProtein Type
Origin
Source
Purity
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Purification tag / Conjugate
- This Kallikrein 1 protein is labelled with His tag.
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Purpose
- Recombinant Mouse Kallikrein 1/KLK1 Protein (His Tag)
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Sequence
- Pro19-Asp261
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Characteristics
- Recombinant Mouse Kallikrein-1 is produced by our Mammalian expression system and the target gene encoding Pro19-Asp261 is expressed with a 6His tag at the C-terminus.
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Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Please refer to the printed manual for detailed information.
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Buffer
- Lyophilized from a 0.2 μm filtered solution of 20 mM Tris,150 mM NaCl, pH 7.5.
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Storage
- 4 °C,-20 °C,-80 °C
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Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- Kallikrein 1 (KLK1)
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Alternative Name
- Kallikrein 1/KLK1
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Background
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Background: Kallikreins belongs to the family of trypsin-like serine proteases, many of which are associated with a variety of cancers. Kallikrein 1 (KLK1) is also known as tissue kallikrein and urinary kallikrein. KLK1 is synthesized as a 261 amino acid (aa) protein that contains a 18 aa signal peptide and a 241 aa proprotein. An important physiological function of KLK1 cleaves Met-Lys and Arg-Ser bonds in kininogen to release Lys-bradykinin. Kinins regulate vasodilation, blood pressure reduction, smooth muscle relaxation and contraction, pain induction and inflammation.
Synonym: Glandular kallikrein K1, KAL-B, Renal kallikrein, Tissue kallikrein-6, mGK-6
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Molecular Weight
- 27.9 kDa
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UniProt
- P15947
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Pathways
- Complement System
Target
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