Kallikrein 7 Protein (KLK7) (His tag)
Quick Overview for Kallikrein 7 Protein (KLK7) (His tag) (ABIN7319371)
Target
See all Kallikrein 7 (KLK7) ProteinsProtein Type
Origin
Source
Purity
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Purification tag / Conjugate
- This Kallikrein 7 protein is labelled with His tag.
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Purpose
- Recombinant Human Kallikrein 7/KLK7 Protein (His Tag)
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Sequence
- Glu23-His252
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Characteristics
- Recombinant Human Kallikrein 7 is produced by our Mammalian expression system and the target gene encoding Glu23-His252 is expressed with a 6His tag at the C-terminus.
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Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
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Kallikrein 7 (KLK7) protein (His tag)
KLK7 Origin: Mouse Host: Human Cells Recombinant > 95 % as determined by SDS-PAGE
Kallikrein 7 (KLK7) (Active) protein (His tag)KLK7 Origin: Mouse Host: HEK-293 Cells Recombinant > (71.4+26) % as determined by SDS-PAGE Active
Kallikrein 7 (KLK7) (AA 1-253) protein (GST tag)KLK7 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Kallikrein 7 (KLK7) (AA 1-181) protein (His tag)KLK7 Origin: Human Host: Baculovirus infected Insect Cells Recombinant > 95% by SDS-PAGE SDS
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Restrictions
- For Research Use only
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Format
- Frozen, Liquid
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Buffer
- Supplied as a 0.2 μm filtered solution of 20 mM HEPES, 150 mM NaCl, pH 7.5.
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Storage
- -20 °C
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Storage Comment
- Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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- Kallikrein 7 (KLK7)
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Alternative Name
- Kallikrein 7/KLK7
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Background
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Background: Human Kallikrein 7 is a member of the tissue kallikrein family of extracellular serine proteases that is made up of 15 members. It is predominantly expressed in the skin. A major physiological function of Kallikrein 7 is to regulate the desquamation process (the shedding of corneocytes from the outer layer of the epidermis) through proteolysis of the intercellular adhesive structures between corneocytes. Dysregulation of Kallikrein 7 has been linked to several inflammatory skin diseases including atopic dermatitis, psoriasis, and Netherton syndrome. Studies have shown that Kallikrein 5 is a potential physiological activator for Kallikrein 7. The proform of Kallikrein 7 can be activated by thermolysin.
Synonym: Kallikrein-7, hK7, Serine Protease 6, Stratum Corneum Chymotryptic Enzyme, hSCCE, KLK7, PRSS6, SCCE
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Molecular Weight
- 26.2 kDa
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UniProt
- P49862
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Pathways
- Complement System
Target
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